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    ACAT2 acetyl-CoA acetyltransferase 2 [ Sus scrofa (pig) ]

    Gene ID: 100152303, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ACAT2provided by VGNC
    Official Full Name
    acetyl-CoA acetyltransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:85005
    See related
    Ensembl:ENSSSCG00000004049
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in liver (RPKM 22.0), subcutaneous adipose (RPKM 19.9) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See ACAT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (7600616..7612861, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (9399574..9411820, complement)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene PARN like ribonuclease domain containing exonuclease 1 Neighboring gene mitochondrial ribosomal protein L18 Neighboring gene t-complex 1 Neighboring gene WT1 associated protein Neighboring gene translation initiation factor IF-2 Neighboring gene superoxide dismutase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. An approach to identify SNPs in the gene encoding acetyl-CoA acetyltransferase-2 (ACAT-2) and their proposed role in metabolic processes in pig. Sodhi SS, et al. PLoS One, 2014. PMID 25050817, Free PMC Article
    2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ACAT2 might contribute more to metabolic processes than ACAA2 in swine.
      Title: An approach to identify SNPs in the gene encoding acetyl-CoA acetyltransferase-2 (ACAT-2) and their proposed role in metabolic processes in pig.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables acetyl-CoA C-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acetyl-CoA acetyltransferase, cytosolic
    Names
    Acetyl-Coenzyme A acetyltransferase 2
    sterol O-acyltransferase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      7600616..7612861 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001928345.4 → XP_001928380.1  acetyl-CoA acetyltransferase, cytosolic

      See identical proteins and their annotated locations for XP_001928380.1

      UniProtKB/TrEMBL
      A0A0B8RZS7, A0A287AHQ0, A0A4X1VWU7, A0A8D1UIK9
      Related
      ENSSSCP00000043380.1, ENSSSCT00000039899.2
      Conserved Domains (2) summary
      PRK05790
      Location:8 → 396
      PRK05790; putative acyltransferase; Provisional
      cd00751
      Location:9 → 396
      thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...
    Nucleotide Protein Strain
    Heading Accession and Version

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