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    mRpS14 mitochondrial ribosomal protein S14 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 117414, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mRpS14provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein S14provided by FlyBase
    Primary source
    FLYBASE:FBgn0044030
    Locus tag
    Dmel_CG32531
    See related
    AllianceGenome:FB:FBgn0044030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg12211; CG12211; CG32531; Dmel\CG32531; MRP-S14; mRPS14; MrpS14; S14
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial small ribosomal subunit. Is expressed in several structures, including adult heart; anterior endoderm; embryonic/larval midgut; embryonic/larval muscle cell; and extended germ band embryo. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 38. Orthologous to human MRPS14 (mitochondrial ribosomal protein S14). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See mRpS14 in Genome Data Viewer
    Location:
    18C7-18C7; 1-62 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19479382..19480238, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19373415..19374271, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene kekkon 5 Neighboring gene long non-coding RNA:CR43260 Neighboring gene uncharacterized protein Neighboring gene N(alpha)-acetyltransferase 15/16 Neighboring gene narya Neighboring gene pacman

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic variation in the shape of cold-survival curves in a single fly population suggests potential for selection from climate variability. Teets NM, et al. J Evol Biol, 2018 Apr. PMID 29345010
    2. A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. Koc EC, et al. J Biol Chem, 2000 Oct 20. PMID 10938081
    3. Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families. Sanjuán R, et al. Mol Biol Evol, 2001 Mar. PMID 11230534
    4. Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Hong X, et al. Proc Natl Acad Sci U S A, 2009 Sep 1. PMID 19706460, Free PMC Article
    5. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial small ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial ribosomal protein S14
    Names
    CG32531-PA
    CG32531-PB
    mRpS14-PA
    mRpS14-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      19479382..19480238 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298509.1 → NP_001285438.1  mitochondrial ribosomal protein S14, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285438.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0JQ38, Q9VWI3
      Conserved Domains (1) summary
      cl00355
      Location:36 → 128
      Ribosomal_S14; Ribosomal protein S14p/S29e

    2. NM_167650.2 → NP_728245.1  mitochondrial ribosomal protein S14, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728245.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0JQ38, Q9VWI3
      Related
      FBpp0074554
      Conserved Domains (1) summary
      cl00355
      Location:36 → 128
      Ribosomal_S14; Ribosomal protein S14p/S29e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VWI3 Q9VWI3

    Gene LinkOut

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