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    p24-1 p24-related-1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32140, updated on 18-Sep-2024

    Summary

    Official Symbol
    p24-1provided by FlyBase
    Official Full Name
    p24-related-1provided by FlyBase
    Primary source
    FLYBASE:FBgn0030341
    Locus tag
    Dmel_CG1967
    See related
    AllianceGenome:FB:FBgn0030341
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-1.45; CG1967; clone 1.45; Dmel\CG1967; p24; p24.1; p26/p24gamma4
    Summary
    Predicted to enable cargo receptor activity. Involved in Wnt protein secretion. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including adult fat body; embryonic epidermis; gut section; proventriculus primordium; and reproductive system. Orthologous to human TMED7-TICAM2 (TMED7-TICAM2 readthrough) and TMED3 (transmembrane p24 trafficking protein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    See p24-1 in Genome Data Viewer
    Location:
    10F1-10F1; 1-37 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11850909..11852530, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11744942..11746563, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45619 Neighboring gene uncharacterized protein Neighboring gene ATP7 Neighboring gene Nardilysin

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cargo receptor activity ISM
    Inferred from Sequence Model
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in Golgi vesicle transport ISM
    Inferred from Sequence Model
    more info
    PubMed 
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 

    General protein information

    Preferred Names
    p24-related-1
    Names
    CG1967-PA
    CG1967-PB
    p24-1-PA
    p24-1-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      11850909..11852530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132526.4NP_572754.1  p24-related-1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572754.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYT6
      Related
      FBpp0073441
      Conserved Domains (1) summary
      pfam01105
      Location:21197
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD
    2. NM_001272536.1NP_001259465.1  p24-related-1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259465.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYT6
      Conserved Domains (1) summary
      pfam01105
      Location:21197
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD