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    CG16890 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34781, updated on 10-May-2024

    Summary

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    Official Symbol
    CG16890provided by FlyBase
    Primary source
    FLYBASE:FBgn0028932
    Locus tag
    Dmel_CG16890
    See related
    AllianceGenome:FB:FBgn0028932
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS00797.4; Dmel\CG16890
    Summary
    Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Orthologous to human FRA10AC1 (FRA10A associated CGG repeat 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See CG16890 in Genome Data Viewer
    Location:
    34D1-34D1; 2-49 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13782231..13784338, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13782231..13784338, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR31845 Neighboring gene p38b MAP kinase Neighboring gene antisense RNA:CR44847 Neighboring gene Engulfment ABC Transporter in the ovary Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A multiplexable TALE-based binary expression system for in vivo cellular interaction studies. Toegel M, et al. Nat Commun, 2017 Nov 21. PMID 29162808, Free PMC Article
    2. A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila. Vrailas-Mortimer A, et al. Dev Cell, 2011 Oct 18. PMID 22014527, Free PMC Article
    3. Large-scale screen for modifiers of ataxin-3-derived polyglutamine-induced toxicity in Drosophila. VoSSfeldt H, et al. PLoS One, 2012. PMID 23139745, Free PMC Article
    4. Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Kankel MW, et al. Genetics, 2020 Jul. PMID 32345615, Free PMC Article
    5. A genomic response to the yeast transcription factor GAL4 in Drosophila. Liu Y, et al. Fly (Austin), 2008 Mar-Apr. PMID 18820459, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c13783957-13783721 mobile_element_type = transposon:S{}2327

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG16890-PA
    CG16890-PC
    CG16890-PD
    NP_001285909.1
    • non-AUG (CUG) translation initiation
    NP_609671.1
    NP_723837.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13782231..13784338 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298980.1 → NP_001285909.1  uncharacterized protein Dmel_CG16890, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285909.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MT83, X2J600
      Conserved Domains (1) summary
      pfam09725
      Location:32 → 150
      Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

    2. NM_165057.4 → NP_723837.2  uncharacterized protein Dmel_CG16890, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723837.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IP65, Q8MT83, Q9V3M2
      Conserved Domains (1) summary
      pfam09725
      Location:42 → 156
      Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1

    3. NM_135827.4 → NP_609671.1  uncharacterized protein Dmel_CG16890, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609671.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IP65, Q8MT83, Q9V3M2
      Related
      FBpp0080152
      Conserved Domains (1) summary
      pfam09725
      Location:42 → 156
      Fra10Ac1; Folate-sensitive fragile site protein Fra10Ac1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BIB5 Q5BIB5
    Q8MT83 Q8MT83
    Q9V3M2 Q9V3M2
    X2J600 X2J600

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