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    mRpL19 mitochondrial ribosomal protein L19 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41028, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mRpL19provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein L19provided by FlyBase
    Primary source
    FLYBASE:FBgn0037608
    Locus tag
    Dmel_CG8039
    See related
    AllianceGenome:FB:FBgn0037608
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8039; Dmel\CG8039; L19; mRPL19; RpL19
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in several structures, including embryonic Malpighian tubule; embryonic/larval muscle system; extended germ band embryo; gut section; and visceral muscle primordium. Orthologous to human MRPL19 (mitochondrial ribosomal protein L19). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See mRpL19 in Genome Data Viewer
    Location:
    85A5-85A5; 3-48 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8674109..8675196)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4499831..4500918)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene pink Neighboring gene transfer RNA:Tyrosine-GTA 1-7 Neighboring gene transfer RNA:Tyrosine-GTA 1-8 Neighboring gene uncharacterized protein Neighboring gene Unc50 RNA binding protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3. Gajan A, et al. Epigenetics Chromatin, 2016. PMID 26848313, Free PMC Article
    2. Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function. Barnes VL, et al. BMC Biochem, 2010 Jul 9. PMID 20618965, Free PMC Article
    3. Cardiomyopathy is associated with ribosomal protein gene haplo-insufficiency in Drosophila melanogaster. Casad ME, et al. Genetics, 2011 Nov. PMID 21890737, Free PMC Article
    4. Protein synthesis and degradation are essential to regulate germline stem cell homeostasis in Drosophila testes. Yu J, et al. Development, 2016 Aug 15. PMID 27471256
    5. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of mitochondrial large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial ribosomal protein L19
    Names
    CG8039-PA
    mRpL19-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8674109..8675196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079560.5 → NP_524284.1  mitochondrial ribosomal protein L19 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524284.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VHN6
      Related
      FBpp0081384
      Conserved Domains (1) summary
      cl00406
      Location:94 → 183
      Ribosomal_L19; Ribosomal protein L19
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHN6.1 Q9VHN6

    Gene LinkOut

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