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    CG6067 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31529, updated on 28-Oct-2024

    Summary

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    Official Symbol
    CG6067provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029828
    Locus tag
    Dmel_CG6067
    See related
    AllianceGenome:FB:FBgn0029828
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6067; SPH254
    Summary
    Predicted to be involved in innate immune response. Predicted to be active in extracellular space. Is expressed in adult head. [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    all
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    Genomic context

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    See CG6067 in Genome Data Viewer
    Location:
    5D1-5D1; 1-15 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5955629..5958283)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5849662..5852316)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene female sterile (1) M3 Neighboring gene Glutamate receptor interacting protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Toll and Imd pathways are the major regulators of the immune response in Drosophila. De Gregorio E, et al. EMBO J, 2002 Jun 3. PMID 12032070, Free PMC Article
    2. Reproductive status alters transcriptomic response to infection in female Drosophila melanogaster. Short SM, et al. G3 (Bethesda), 2013 May 20. PMID 23550122, Free PMC Article
    3. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article
    4. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
    5. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    NOT enables serine-type endopeptidase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6067-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5955629..5958283
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132055.2 → NP_572283.1  uncharacterized protein Dmel_CG6067 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572283.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DMH6, Q9W452
      Related
      FBpp0070829
      Conserved Domains (1) summary
      cl21584
      Location:62 → 174
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MT25 Q8MT25
    Q9W452 Q9W452

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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