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    Or8b12i olfactory receptor family 8 subfamily B member 12I [ Mus musculus (house mouse) ]

    Gene ID: 57251, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Or8b12iprovided by MGI
    Official Full Name
    olfactory receptor family 8 subfamily B member 12Iprovided by MGI
    Primary source
    MGI:MGI:3030704
    See related
    Ensembl:ENSMUSG00000066899 AllianceGenome:MGI:3030704
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr72; Olfr870; MOR141-1
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
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    Genomic context

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    See Or8b12i in Genome Data Viewer
    Location:
    9 A3; 9 7.48 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (20081930..20082865, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (20170634..20171569, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23450 Neighboring gene olfactory receptor family 7 subfamily E member 174 Neighboring gene olfactory receptor family 7 subfamily E member 175 Neighboring gene STARR-seq mESC enhancer starr_23451 Neighboring gene STARR-seq mESC enhancer starr_23452 Neighboring gene olfactory receptor family 7 subfamily H member 8 Neighboring gene STARR-seq mESC enhancer starr_23453 Neighboring gene STARR-seq mESC enhancer starr_23454 Neighboring gene olfactory receptor family 7 subfamily E member 176 Neighboring gene predicted gene, 25425

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates. Rouquier S, et al. Proc Natl Acad Sci U S A, 2000 Mar 14. PMID 10706615, Free PMC Article
    2. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    3. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    4. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
    5. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor family 8 subfamily B member 12I
    Names
    GA_x6K02T2PVTD-13912679-13911744
    olfactory receptor 72
    olfactory receptor 870
    olfactory receptor MOR141-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146904.1 → NP_667115.1  olfactory receptor family 8 subfamily B member 12I

      See identical proteins and their annotated locations for NP_667115.1

      Status: PROVISIONAL

      Source sequence(s)
      AY073184
      Consensus CDS
      CCDS22872.1
      UniProtKB/TrEMBL
      Q8VGG4, Q9JM16
      Related
      ENSMUSP00000091405.2, ENSMUST00000086476.3
      Conserved Domains (2) summary
      pfam00001
      Location:41 → 290
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31 → 311
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      20081930..20082865 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_020500.1: Suppressed sequence

      Description
      NM_020500.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

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