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    Klra10 killer cell lectin-like receptor subfamily A, member 10 [ Mus musculus (house mouse) ]

    Gene ID: 16628, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Klra10provided by MGI
    Official Full Name
    killer cell lectin-like receptor subfamily A, member 10provided by MGI
    Primary source
    MGI:MGI:1321093
    See related
    Ensembl:ENSMUSG00000072718 AllianceGenome:MGI:1321093
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ly49J; Ly49i2
    Summary
    Predicted to enable signaling receptor activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Klra10 in Genome Data Viewer
    Location:
    6 F3; 6 63.44 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (130243330..130260698, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (130269194..130283647, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene killer cell lectin-like receptor subfamily A, member 9 Neighboring gene predicted gene, 52487 Neighboring gene killer cell lectin-like receptor, subfamily A, member 7 Neighboring gene killer cell lectin-like receptor subfamily A, member 13, pseudogene Neighboring gene predicted gene, 24072

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Expression analysis of new Ly49 genes: most transcripts of Ly49j lack the transmembrane domain. McQueen KL, et al. Immunogenetics, 1999 Jul. PMID 10369927
    2. Localization of five new Ly49 genes, including three closely related to Ly49c. McQueen KL, et al. Immunogenetics, 1998 Aug. PMID 9683662
    3. A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice. Makrigiannis AP, et al. Genomics, 2002 Mar. PMID 11863373
    4. Class I MHC-binding characteristics of the 129/J Ly49 repertoire. Makrigiannis AP, et al. J Immunol, 2001 Apr 15. PMID 11290784
    5. The ly49 gene family. A brief guide to the nomenclature, genetics, and role in intracellular infection. Schenkel AR, et al. Front Immunol, 2013. PMID 23596445, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    killer cell lectin-like receptor subfamily A, member 10
    Names
    natural killer cell receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008459.2 → NP_032485.2  killer cell lectin-like receptor subfamily A, member 10

      See identical proteins and their annotated locations for NP_032485.2

      Status: VALIDATED

      Source sequence(s)
      AF110492
      Consensus CDS
      CCDS20600.1
      UniProtKB/TrEMBL
      C7SF18, Q9R1G6
      Related
      ENSMUSP00000107651.2, ENSMUST00000112020.2
      Conserved Domains (2) summary
      cd03593
      Location:145 → 257
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:40 → 157
      Ly49; Ly49-like protein, N-terminal region

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      130243330..130260698 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165886.1 → XP_036021779.1  killer cell lectin-like receptor subfamily A, member 10 isoform X1

      Conserved Domains (2) summary
      cd03593
      Location:145 → 259
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:40 → 157
      Ly49; Ly49-like protein, N-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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