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    IRAIN IGF1R antisense imprinted non-protein coding RNA [ Homo sapiens (human) ]

    Gene ID: 104472848, updated on 17-Sep-2024

    Summary

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    Official Symbol
    IRAINprovided by HGNC
    Official Full Name
    IGF1R antisense imprinted non-protein coding RNAprovided by HGNC
    Primary source
    HGNC:HGNC:50365
    See related
    MIM:619212; AllianceGenome:HGNC:50365
    Gene type
    ncRNA
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IGF1RAS; IGF1R-AS
    Summary
    This gene expresses a long non-coding RNA in antisense to the insulin-like growth factor type I receptor (IGF1R) gene. This transcript is imprinted and expressed from the paternal allele. It interacts with chromatin and may promote long-range DNA interactions that influence the regulation of gene expression. [provided by RefSeq, Nov 2015]
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    Genomic context

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    See IRAIN in Genome Data Viewer
    Location:
    15q26.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (98645863..98650787, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (96410234..96415156, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (99189092..99194016, complement)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_42822 Neighboring gene long intergenic non-protein coding RNA 2351 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr15:98957206-98958405 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:98959168-98959668 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:98959669-98960169 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:98964233-98964808 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10139 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:98965386-98965961 Neighboring gene Sharpr-MPRA regulatory regions 4169 and 6096 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6853 Neighboring gene zinc finger CCHC-type containing 9 pseudogene Neighboring gene protein FAM169B Neighboring gene ReSE screen-validated silencer GRCh37_chr15:99031875-99032074 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:99056319-99056501 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99122390-99122890 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99122891-99123391 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99135615-99136114 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99143220-99143720 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99143721-99144221 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99148269-99148769 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6855 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6854 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:99189870-99190491 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6856 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6857 Neighboring gene Sharpr-MPRA regulatory region 7544 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:99204502-99205312 Neighboring gene Sharpr-MPRA regulatory region 1749 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:99211661-99212860 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr15:99213965-99214690 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99243457-99243958 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:99243959-99244458 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:99247546-99247726 Neighboring gene insulin like growth factor 1 receptor Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:99256117-99256819 Neighboring gene VISTA enhancer hs1932 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:99277618-99278148 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:99301249-99301750 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:99301751-99302250 Neighboring gene uncharacterized LOC124903560 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:99316261-99316843 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:99316844-99317425 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:99319525-99320432 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:99320433-99321339 Neighboring gene microRNA 4714

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_045221.1 RefSeqGene

      Range
      5435..10359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_1064

    RNA

    1. NR_126453.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC118658

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      98645863..98650787 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      96410234..96415156 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials