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    Armt1 acidic residue methyltransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 73419, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Armt1provided by MGI
    Official Full Name
    acidic residue methyltransferase 1provided by MGI
    Primary source
    MGI:MGI:1920669
    See related
    Ensembl:ENSMUSG00000061759 AllianceGenome:MGI:1920669
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700052N19Rik
    Summary
    Predicted to enable enzyme binding activity; methyltransferase activity; and phosphatase activity. Predicted to be involved in DNA damage response. Orthologous to human ARMT1 (acidic residue methyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 19.5), liver E14 (RPKM 6.3) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Armt1 in Genome Data Viewer
    Location:
    10 A1; 10 2.06 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (4382572..4405140)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (4429275..4455140)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25640 Neighboring gene A kinase anchor protein 12 Neighboring gene predicted gene, 40592 Neighboring gene STARR-seq mESC enhancer starr_25637 Neighboring gene STARR-positive B cell enhancer ABC_E11428 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5999414-5999597 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5988889-5989072 Neighboring gene STARR-seq mESC enhancer starr_25630 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:5958087-5958270 Neighboring gene zinc finger and BTB domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E2315 Neighboring gene required for meiotic nuclear division 1 homolog Neighboring gene STARR-seq mESC enhancer starr_25628 Neighboring gene coiled-coil domain containing 170 Neighboring gene predicted gene, 22739 Neighboring gene STARR-seq mESC enhancer starr_25624 Neighboring gene glutathione S-transferase, pi 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC102037

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables S-adenosylmethionine-dependent methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables fructose 6-phosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fructose-1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein carboxyl O-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein carboxyl O-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein-glutamate O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA damage response ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in DNA damage response ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    damage-control phosphatase ARMT1
    Names
    UPF0364 protein C6orf211 homolog
    protein-glutamate O-methyltransferase
    sugar phosphate phosphatase ARMT1
    NP_077223.2
    XP_011241402.1
    XP_011241403.1
    XP_030101175.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024261.2 → NP_077223.2  damage-control phosphatase ARMT1

      See identical proteins and their annotated locations for NP_077223.2

      Status: VALIDATED

      Source sequence(s)
      BC099894, BU148062
      Consensus CDS
      CCDS56676.1
      UniProtKB/Swiss-Prot
      A6H630, Q499H1, Q99M05, Q9D9L4
      Related
      ENSMUSP00000093581.5, ENSMUST00000095893.11
      Conserved Domains (1) summary
      pfam01937
      Location:20 → 417
      DUF89; Protein of unknown function DUF89

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      4382572..4405140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243100.4 → XP_011241402.1  damage-control phosphatase ARMT1 isoform X1

      See identical proteins and their annotated locations for XP_011241402.1

      Conserved Domains (1) summary
      pfam01937
      Location:50 → 331
      DUF89; Protein of unknown function DUF89

    2. XM_030245315.2 → XP_030101175.1  damage-control phosphatase ARMT1 isoform X2

      Conserved Domains (1) summary
      pfam01937
      Location:1 → 298
      DUF89; Protein of unknown function DUF89

    3. XM_011243101.4 → XP_011241403.1  damage-control phosphatase ARMT1 isoform X1

      See identical proteins and their annotated locations for XP_011241403.1

      Conserved Domains (1) summary
      pfam01937
      Location:50 → 331
      DUF89; Protein of unknown function DUF89
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6H630.1 GenPept UniProtKB/Swiss-Prot:A6H630

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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