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    Ccdc74a coiled-coil domain containing 74A [ Mus musculus (house mouse) ]

    Gene ID: 72315, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Ccdc74aprovided by MGI
    Official Full Name
    coiled-coil domain containing 74Aprovided by MGI
    Primary source
    MGI:MGI:1919565
    See related
    Ensembl:ENSMUSG00000041617 AllianceGenome:MGI:1919565
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310015A05Rik
    Summary
    Orthologous to human CCDC74A (coiled-coil domain containing 74A) and CCDC74B (coiled-coil domain containing 74B). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in testis adult (RPKM 36.0), cerebellum adult (RPKM 17.7) and 9 other tissues See more
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    Genomic context

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    See Ccdc74a in Genome Data Viewer
    Location:
    16 A3; 16 10.94 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (17464340..17468602)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (17646454..17650738)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 Neighboring gene STARR-seq mESC enhancer starr_40258 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:17619324-17619507 Neighboring gene sphingomyelin phosphodiesterase 4 Neighboring gene STARR-seq mESC enhancer starr_40259 Neighboring gene mediator complex subunit 15 Neighboring gene calcyclin binding protein pseudogene Neighboring gene ribosomal protein L26, pseudogene 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 74B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166164.2 → NP_001159636.1  coiled-coil domain-containing protein 74B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC115733
      Consensus CDS
      CCDS49782.1
      UniProtKB/TrEMBL
      E9Q9U8
      Related
      ENSMUSP00000049541.4, ENSMUST00000056962.11
      Conserved Domains (2) summary
      pfam14916
      Location:50 → 105
      CCDC92; Coiled-coil domain of unknown function
      pfam14917
      Location:209 → 326
      CCDC74_C; Coiled coil protein 74, C terminal

    2. NM_001418864.1 → NP_001405793.1  coiled-coil domain-containing protein 74B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC115733

    RNA

    1. NR_184835.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC115733
      Related
      ENSMUST00000182117.8

    2. NR_184836.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC115733

    3. NR_184837.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC115733
      Related
      ENSMUST00000182671.8

    4. NR_184838.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC115733

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      17464340..17468602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522601.5 → XP_006522664.2  coiled-coil domain-containing protein 74B isoform X1

      Conserved Domains (2) summary
      pfam14916
      Location:50 → 105
      CCDC92; Coiled-coil domain of unknown function
      pfam14917
      Location:209 → 307
      CCDC74_C; Coiled coil protein 74, C terminal

    2. XM_006522602.5 → XP_006522665.2  coiled-coil domain-containing protein 74B isoform X2

      Conserved Domains (1) summary
      pfam14916
      Location:50 → 105
      CCDC92; Coiled-coil domain of unknown function

    3. XM_006522604.5 → XP_006522667.2  coiled-coil domain-containing protein 74B isoform X4

      Conserved Domains (1) summary
      pfam14916
      Location:50 → 105
      CCDC92; Coiled-coil domain of unknown function
    Nucleotide Protein Strain
    Heading Accession and Version

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