U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ppp1r27 protein phosphatase 1, regulatory subunit 27 [ Mus musculus (house mouse) ]

    Gene ID: 68701, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ppp1r27provided by MGI
    Official Full Name
    protein phosphatase 1, regulatory subunit 27provided by MGI
    Primary source
    MGI:MGI:1915951
    See related
    Ensembl:ENSMUSG00000025129 AllianceGenome:MGI:1915951
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    toonin; Dysfip1; 1110033I14Rik
    Summary
    Predicted to enable phosphatase binding activity. Orthologous to human PPP1R27 (protein phosphatase 1 regulatory subunit 27). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in mammary gland adult (RPKM 26.3), testis adult (RPKM 11.5) and 2 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Ppp1r27 in Genome Data Viewer
    Location:
    11 E2; 11 84.26 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (120440801..120441958, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (120549975..120551132, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene glucagon receptor Neighboring gene MAPK regulated corepressor interacting protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E8476 Neighboring gene prolyl 4-hydroxylase, beta polypeptide Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:120434472-120434581 Neighboring gene Rho GDP dissociation inhibitor alpha

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phosphatase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein phosphatase 1 regulatory subunit 27
    Names
    dysferlin-interacting protein 1
    ortholog of human dysferlin interacting protein 1 (toonin) DYSFP1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026814.3 → NP_081090.1  protein phosphatase 1 regulatory subunit 27

      See identical proteins and their annotated locations for NP_081090.1

      Status: PROVISIONAL

      Source sequence(s)
      AK004064
      Consensus CDS
      CCDS36392.1
      UniProtKB/Swiss-Prot
      A2ABX5, Q9D119
      Related
      ENSMUSP00000026121.3, ENSMUST00000026121.3
      Conserved Domains (3) summary
      cd00204
      Location:38 → 147
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:38 → 127
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:63 → 94
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      120440801..120441958 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D119.1 GenPept UniProtKB/Swiss-Prot:Q9D119

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools