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    PRR15 proline rich 15 [ Homo sapiens (human) ]

    Gene ID: 222171, updated on 17-Sep-2024

    Summary

    Official Symbol
    PRR15provided by HGNC
    Official Full Name
    proline rich 15provided by HGNC
    Primary source
    HGNC:HGNC:22310
    See related
    Ensembl:ENSG00000176532 MIM:618344; AllianceGenome:HGNC:22310
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in colon (RPKM 29.0), small intestine (RPKM 15.6) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PRR15 in Genome Data Viewer
    Location:
    7p14.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (29563835..29567295)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (29701617..29705075)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (29603451..29606911)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene chimerin 2 Neighboring gene Nanog homeobox pseudogene 4 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr7:29327971-29328748 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:29343002-29343502 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:29343503-29344003 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:29349448-29350016 Neighboring gene NANOG hESC enhancer GRCh37_chr7:29364906-29365431 Neighboring gene MPRA-validated peak6458 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:29414107-29414613 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:29456733-29457232 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:29456231-29456732 Neighboring gene PRR15 divergent transcript Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:29605074-29605937 Neighboring gene GTF3C6 pseudogene 3 Neighboring gene Sharpr-MPRA regulatory region 12919 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:29688411-29689013 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:29689014-29689615 Neighboring gene TMSB4X pseudogene 3 Neighboring gene MIR550A3 host gene Neighboring gene microRNA 550a-3

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001329996.2NP_001316925.1  proline-rich protein 15

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AC007255
      Consensus CDS
      CCDS5421.1
      UniProtKB/Swiss-Prot
      Q8IV56
      UniProtKB/TrEMBL
      A4D1A1
      Conserved Domains (1) summary
      pfam15321
      Location:13109
      ATAD4; ATPase family AAA domain containing 4
    2. NM_001329997.1NP_001316926.1  proline-rich protein 15

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
      Source sequence(s)
      AC007255
      Consensus CDS
      CCDS5421.1
      UniProtKB/Swiss-Prot
      Q8IV56
      UniProtKB/TrEMBL
      A4D1A1
      Conserved Domains (1) summary
      pfam15321
      Location:13109
      ATAD4; ATPase family AAA domain containing 4
    3. NM_175887.3NP_787083.1  proline-rich protein 15

      See identical proteins and their annotated locations for NP_787083.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
      Source sequence(s)
      BC029131
      Consensus CDS
      CCDS5421.1
      UniProtKB/Swiss-Prot
      Q8IV56
      UniProtKB/TrEMBL
      A4D1A1
      Related
      ENSP00000317836.2, ENST00000319694.3
      Conserved Domains (1) summary
      pfam15321
      Location:13109
      ATAD4; ATPase family AAA domain containing 4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      29563835..29567295
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011515199.2XP_011513501.1  proline-rich protein 15 isoform X1

      See identical proteins and their annotated locations for XP_011513501.1

      UniProtKB/Swiss-Prot
      Q8IV56
      UniProtKB/TrEMBL
      A4D1A1
      Conserved Domains (1) summary
      pfam15321
      Location:13109
      ATAD4; ATPase family AAA domain containing 4
    2. XM_011515198.2XP_011513500.1  proline-rich protein 15 isoform X1

      See identical proteins and their annotated locations for XP_011513500.1

      UniProtKB/Swiss-Prot
      Q8IV56
      UniProtKB/TrEMBL
      A4D1A1
      Conserved Domains (1) summary
      pfam15321
      Location:13109
      ATAD4; ATPase family AAA domain containing 4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      29701617..29705075
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054357569.1XP_054213544.1  proline-rich protein 15 isoform X1

    2. XM_054357568.1XP_054213543.1  proline-rich protein 15 isoform X1