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    Cryzl2 crystallin zeta like 2 [ Mus musculus (house mouse) ]

    Gene ID: 226527, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Cryzl2provided by MGI
    Official Full Name
    crystallin zeta like 2provided by MGI
    Primary source
    MGI:MGI:2448516
    See related
    Ensembl:ENSMUSG00000033488 AllianceGenome:MGI:2448516
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable oxidoreductase activity. Located in mitochondrion. Orthologous to human CRYZL2P (crystallin zeta like 2, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in kidney adult (RPKM 78.4), adrenal adult (RPKM 11.4) and 7 other tissues See more
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    Genomic context

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    See Cryzl2 in Genome Data Viewer
    Location:
    1 H1; 1 67.99 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (157280082..157317570)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (157455718..157490000)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RAS protein activator like 2 Neighboring gene RIKEN cDNA 2810025M15 gene Neighboring gene STARR-positive B cell enhancer ABC_E5829 Neighboring gene STARR-seq mESC enhancer starr_02765 Neighboring gene GABA(A) receptor-associated protein-like 2 pseudogene 1_1522.1 Neighboring gene STARR-seq mESC enhancer starr_02769 Neighboring gene STARR-seq mESC enhancer starr_02770 Neighboring gene predicted gene, 57801 Neighboring gene predicted gene 15486 Neighboring gene SEC16 homolog B, endoplasmic reticulum export factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of new ciliary signaling pathways in the brain and insights into neurological disorders. Loukil A, et al. bioRxiv, 2023 Dec 21. PMID 38187761, Free PMC Article
    2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    quinone oxidoreductase-like protein 2
    Names
    quinone reductase-like 2
    zeta-crystallin homolog 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033284.3 → NP_001028456.1  quinone oxidoreductase-like protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001028456.1

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108
      Consensus CDS
      CCDS15399.1
      UniProtKB/Swiss-Prot
      Q3UAM2, Q3UNZ8
      Related
      ENSMUSP00000044945.5, ENSMUST00000046743.11
      Conserved Domains (1) summary
      cd08241
      Location:27 → 347
      QOR1; Quinone oxidoreductase (QOR)

    2. NM_001356418.2 → NP_001343347.1  quinone oxidoreductase-like protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108
      Consensus CDS
      CCDS87898.1
      UniProtKB/TrEMBL
      A0A0A6YWV6
      Related
      ENSMUSP00000141717.2, ENSMUST00000193791.6
      Conserved Domains (1) summary
      cl16912
      Location:27 → 169
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    3. NM_001356419.2 → NP_001343348.1  quinone oxidoreductase-like protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108
      Consensus CDS
      CCDS87899.1
      Related
      ENSMUSP00000113664.2, ENSMUST00000119891.7
      Conserved Domains (1) summary
      cl16912
      Location:27 → 167
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    4. NM_001421427.1 → NP_001408356.1  quinone oxidoreductase-like protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108

    5. NM_001421432.1 → NP_001408361.1  quinone oxidoreductase-like protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108

    6. NM_001421433.1 → NP_001408362.1  quinone oxidoreductase-like protein 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108

    7. NM_001421434.1 → NP_001408363.1  quinone oxidoreductase-like protein 2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108

    8. NM_001421435.1 → NP_001408364.1  quinone oxidoreductase-like protein 2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC119897, AC161108

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      157280082..157317570
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164051.1 → XP_036019944.1  quinone oxidoreductase-like protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3UAM2, Q3UNZ8
      Conserved Domains (1) summary
      cd08241
      Location:27 → 347
      QOR1; Quinone oxidoreductase (QOR)

    2. XM_017319995.1 → XP_017175484.1  quinone oxidoreductase-like protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q3UAM2, Q3UNZ8
      Conserved Domains (1) summary
      cd08241
      Location:27 → 347
      QOR1; Quinone oxidoreductase (QOR)

    3. XM_030253320.1 → XP_030109180.1  quinone oxidoreductase-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A0A6YWV6
      Conserved Domains (1) summary
      cl16912
      Location:27 → 169
      MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

    4. XM_030253318.1 → XP_030109178.1  quinone oxidoreductase-like protein 2 isoform X2

      Conserved Domains (1) summary
      cd08241
      Location:27 → 252
      QOR1; Quinone oxidoreductase (QOR)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UNZ8.1 GenPept UniProtKB/Swiss-Prot:Q3UNZ8

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