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    Spats1 spermatogenesis associated, serine-rich 1 [ Mus musculus (house mouse) ]

    Gene ID: 71020, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Spats1provided by MGI
    Official Full Name
    spermatogenesis associated, serine-rich 1provided by MGI
    Primary source
    MGI:MGI:1918270
    See related
    Ensembl:ENSMUSG00000023935 AllianceGenome:MGI:1918270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ddip; Srsp1; 1700011H05Rik; 4933400B06Rik
    Summary
    Is expressed in nervous system and testis. Orthologous to human SPATS1 (spermatogenesis associated serine rich 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 3.7), frontal lobe adult (RPKM 0.6) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Spats1 in Genome Data Viewer
    Location:
    17 B3; 17 22.44 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (45754156..45785864, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (45443230..45475108, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8677 Neighboring gene cell division cycle 5-like Neighboring gene RIKEN cDNA B230354K17 gene Neighboring gene STARR-positive B cell enhancer ABC_E5612 Neighboring gene STARR-seq mESC enhancer starr_42621 Neighboring gene STARR-seq mESC enhancer starr_42624 Neighboring gene ribosomal protein L21 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:45625569-45626099 Neighboring gene STARR-seq mESC enhancer starr_42626 Neighboring gene STARR-positive B cell enhancer ABC_E4215 Neighboring gene STARR-positive B cell enhancer ABC_E9052 Neighboring gene alanyl-tRNA synthetase 2, mitochondrial Neighboring gene t-complex-associated testis expressed 1 Neighboring gene transmembrane protein 151B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. SPATS1 (spermatogenesis-associated, serine-rich 1) is not essential for spermatogenesis and fertility in mouse. Capoano CA, et al. PLoS One, 2021. PMID 33945571, Free PMC Article
    2. Identification and characterization of SRSP1, a rat gene differentially expressed during spermatogenesis and coding for a serine stretch-containing protein. Geisinger A, et al. Cytogenet Genome Res, 2002. PMID 12826748
    3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2)  1 citation
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis-associated serine-rich protein 1
    Names
    dvl2-DEP domain-interacting protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357831.1 → NP_001344760.1  spermatogenesis-associated serine-rich protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC163677
      Consensus CDS
      CCDS89103.1
      Related
      ENSMUSP00000156716.2, ENSMUST00000233553.2
      Conserved Domains (1) summary
      pfam15160
      Location:10 → 255
      SASRP1; Spermatogenesis-associated serine-rich protein 1

    2. NM_001357832.1 → NP_001344761.1  spermatogenesis-associated serine-rich protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC163677, AK005865, AK016586
      Consensus CDS
      CCDS89102.1
      Related
      ENSMUSP00000156469.2, ENSMUST00000233769.2
      Conserved Domains (1) summary
      pfam15160
      Location:10 → 234
      SASRP1; Spermatogenesis-associated serine-rich protein 1

    3. NM_027649.3 → NP_081925.2  spermatogenesis-associated serine-rich protein 1 isoform 1

      See identical proteins and their annotated locations for NP_081925.2

      Status: VALIDATED

      Source sequence(s)
      AK005865, AK016586, AV045867, BC131909
      Consensus CDS
      CCDS50118.1
      UniProtKB/Swiss-Prot
      A2RRY8, Q6VNB9, Q9CUD9, Q9DAG2
      Related
      ENSMUSP00000024731.9, ENSMUST00000024731.9
      Conserved Domains (1) summary
      pfam15160
      Location:10 → 255
      SASRP1; Spermatogenesis-associated serine-rich protein 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      45754156..45785864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160786.1 → XP_036016679.1  spermatogenesis-associated serine-rich protein 1 isoform X1

      Conserved Domains (1) summary
      pfam15160
      Location:10 → 234
      SASRP1; Spermatogenesis-associated serine-rich protein 1

    2. XM_011246605.3 → XP_011244907.1  spermatogenesis-associated serine-rich protein 1 isoform X2

      Conserved Domains (1) summary
      pfam15160
      Location:9 → 103
      SASRP1; Spermatogenesis-associated serine-rich protein 1

    RNA

    1. XR_004939576.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2RRY8.1 GenPept UniProtKB/Swiss-Prot:A2RRY8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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