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    Rpp21 ribonuclease P 21 subunit [ Mus musculus (house mouse) ]

    Gene ID: 67676, updated on 2-Nov-2024

    Summary

    Official Symbol
    Rpp21provided by MGI
    Official Full Name
    ribonuclease P 21 subunitprovided by MGI
    Primary source
    MGI:MGI:1914926
    See related
    Ensembl:ENSMUSG00000024446 AllianceGenome:MGI:1914926
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610037N01Rik
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleolus. Predicted to be part of nucleolar ribonuclease P complex. Orthologous to human RPP21 (ribonuclease P/MRP subunit p21). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 19.9), stomach adult (RPKM 18.6) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rpp21 in Genome Data Viewer
    Location:
    17 B1; 17 19.01 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36566565..36568738, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (36255673..36257846, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene 4252 Neighboring gene non-histone chromosomal protein HMG-14 pseudogene Neighboring gene tripartite motif-containing 39 Neighboring gene histocompatibility 2, M region locus 10.2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribonuclease P RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribonuclease P RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribonuclease P activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to ribonuclease P activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in response to xenobiotic stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA 5'-leader removal IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA 5'-leader removal ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of multimeric ribonuclease P complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleolar ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p21
    Names
    RNaseP protein p21
    ribonuclease P 21kDa subunit
    ribonucleoprotein V
    NP_080584.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026308.2NP_080584.1  ribonuclease P protein subunit p21

      See identical proteins and their annotated locations for NP_080584.1

      Status: PROVISIONAL

      Source sequence(s)
      AK002780
      Consensus CDS
      CCDS28719.1
      UniProtKB/Swiss-Prot
      Q80XY3, Q811B7, Q8R040, Q9CPX1
      Related
      ENSMUSP00000025319.7, ENSMUST00000025319.7
      Conserved Domains (1) summary
      pfam04032
      Location:1396
      Rpr2; RNAse P Rpr2/Rpp21/SNM1 subunit domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      36566565..36568738 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)