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    Ccnyl1 cyclin Y-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 227210, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ccnyl1provided by MGI
    Official Full Name
    cyclin Y-like 1provided by MGI
    Primary source
    MGI:MGI:2138614
    See related
    Ensembl:ENSMUSG00000070871 AllianceGenome:MGI:2138614
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630037P07Rik
    Summary
    Acts upstream of or within flagellated sperm motility; regulation of protein kinase activity; and spermatogenesis. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; mammary gland; and spleen. Orthologous to human CCNYL1 (cyclin Y like 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 21.2), limb E14.5 (RPKM 6.5) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccnyl1 in Genome Data Viewer
    Location:
    1 C2; 1 32.74 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (64729963..64764805)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (64691041..64725646)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene 29152 Neighboring gene RIKEN cDNA 2810408I11 gene Neighboring gene STARR-positive B cell enhancer ABC_E983 Neighboring gene STARR-positive B cell enhancer ABC_E9466 Neighboring gene STARR-positive B cell enhancer ABC_E11072 Neighboring gene STARR-seq mESC enhancer starr_01166 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:64784525-64784634 Neighboring gene frizzled class receptor 5 Neighboring gene pleckstrin homology domain containing, family M, member 3 Neighboring gene leucine rich repeat containing 15 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within flagellated sperm motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cyclin-Y-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001097644.1 → NP_001091113.1  cyclin-Y-like protein 1

      See identical proteins and their annotated locations for NP_001091113.1

      Status: VALIDATED

      Source sequence(s)
      AK079350, AK132782, BE944301, CN668580, DV657169
      Consensus CDS
      CCDS48281.1
      Related
      ENSMUSP00000092499.4, ENSMUST00000094898.5
      Conserved Domains (1) summary
      pfam00134
      Location:124 → 215
      Cyclin_N; Cyclin, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      64729963..64764805
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006495953.4 → XP_006496016.1  cyclin-Y-like protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006496016.1

      UniProtKB/Swiss-Prot
      D3YUJ3, E9Q226
      Conserved Domains (1) summary
      cd20540
      Location:138 → 234
      CYCLIN_CCNY_like; cyclin box found in cyclin-Y (CCNY) family

    2. XM_011238499.3 → XP_011236801.1  cyclin-Y-like protein 1 isoform X1

      UniProtKB/Swiss-Prot
      D3YUJ3, E9Q226
      Related
      ENSMUSP00000109711.2, ENSMUST00000114077.8
      Conserved Domains (1) summary
      pfam00134
      Location:197 → 288
      Cyclin_N; Cyclin, N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D3YUJ3.1 GenPept UniProtKB/Swiss-Prot:D3YUJ3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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