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    OR13A1 olfactory receptor family 13 subfamily A member 1 [ Homo sapiens (human) ]

    Gene ID: 79290, updated on 2-Nov-2024

    Summary

    Official Symbol
    OR13A1provided by HGNC
    Official Full Name
    olfactory receptor family 13 subfamily A member 1provided by HGNC
    Primary source
    HGNC:HGNC:14772
    See related
    Ensembl:ENSG00000256574 AllianceGenome:HGNC:14772
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See OR13A1 in Genome Data Viewer
    Location:
    10q11.21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (45302297..45315608, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (46183344..46196657, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (45798098..45811056, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene cubilin pseudogene 2 Neighboring gene olfactory receptor family 6 subfamily D member 1 pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr10:45839254-45839455 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45869432-45870042 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45870043-45870651 Neighboring gene arachidonate 5-lipoxygenase Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45914387-45915080 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45915081-45915772 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45915801-45916302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45921315-45921815 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45923135-45923798 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45928754-45929292 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:45928214-45928753 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:45933181-45934380 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:45937030-45937261 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45937618-45938388 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45938389-45939157 Neighboring gene uncharacterized LOC102724323 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:45958734-45959933 Neighboring gene uncharacterized LOC105378286 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3321 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45970297-45970798 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45970799-45971298 Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:45998823-45999323

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ16797

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 13A1
    Names
    olfactory receptor OR10-3
    seven transmembrane helix receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004297.3NP_001004297.2  olfactory receptor 13A1

      See identical proteins and their annotated locations for NP_001004297.2

      Status: VALIDATED

      Source sequence(s)
      AK131555, AL512324
      Consensus CDS
      CCDS31188.1
      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8, A0A126GW17
      Related
      ENSP00000451950.1, ENST00000553795.6
      Conserved Domains (1) summary
      cd15232
      Location:43312
      7tmA_OR13-like; olfactory receptor family 13 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      45302297..45315608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047425731.1XP_047281687.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    2. XM_047425730.1XP_047281686.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
      Related
      ENSP00000363522.2, ENST00000374401.3
    3. XM_047425729.1XP_047281685.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    4. XM_017016632.3XP_016872121.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8, A0A126GW17
      Conserved Domains (1) summary
      cd15232
      Location:43312
      7tmA_OR13-like; olfactory receptor family 13 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NW_003315935.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      127062..140376 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054329563.1XP_054185538.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    2. XM_054329561.1XP_054185536.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    3. XM_054329562.1XP_054185537.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      46183344..46196657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054366717.1XP_054222692.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    2. XM_054366716.1XP_054222691.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    3. XM_054366713.1XP_054222688.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    4. XM_054366714.1XP_054222689.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8
    5. XM_054366715.1XP_054222690.1  olfactory receptor 13A1 isoform X1

      UniProtKB/Swiss-Prot
      Q2M3M4, Q5VV57, Q6IFH5, Q6ZMN6, Q8NGR1
      UniProtKB/TrEMBL
      A0A126GVD8