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    Fam227b family with sequence similarity 227, member B [ Mus musculus (house mouse) ]

    Gene ID: 75823, updated on 2-Nov-2024

    Summary

    Official Symbol
    Fam227bprovided by MGI
    Official Full Name
    family with sequence similarity 227, member Bprovided by MGI
    Primary source
    MGI:MGI:1923073
    See related
    Ensembl:ENSMUSG00000027209 AllianceGenome:MGI:1923073
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930525F21Rik
    Summary
    Orthologous to human FAM227B (family with sequence similarity 227 member B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 11.1), large intestine adult (RPKM 2.9) and 11 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Fam227b in Genome Data Viewer
    Location:
    2 F1; 2 61.76 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (125825403..125994048, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (125983473..126152153, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene SECIS binding protein 2-like Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:125602741-125602942 Neighboring gene STARR-positive B cell enhancer ABC_E5976 Neighboring gene STARR-positive B cell enhancer ABC_E7857 Neighboring gene STARR-positive B cell enhancer ABC_E11156 Neighboring gene COP9 signalosome subunit 2 Neighboring gene galactokinase 2 Neighboring gene fibroblast growth factor 7 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:125977713-125977822 Neighboring gene predicted gene, 26496 Neighboring gene DTW domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_05598 Neighboring gene predicted gene, 54149 Neighboring gene STARR-seq mESC enhancer starr_05599 Neighboring gene STARR-seq mESC enhancer starr_05600 Neighboring gene STARR-positive B cell enhancer ABC_E2643 Neighboring gene STARR-seq mESC enhancer starr_05601 Neighboring gene STARR-seq mESC enhancer starr_05602 Neighboring gene STARR-seq mESC enhancer starr_05603 Neighboring gene STARR-positive B cell enhancer mm9_chr2:126188755-126189056 Neighboring gene ATPase, class I, type 8B, member 4 Neighboring gene Brca1 associated protein 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029455.3NP_083731.2  protein FAM227B

      See identical proteins and their annotated locations for NP_083731.2

      Status: VALIDATED

      Source sequence(s)
      AL845292, AL929175
      Consensus CDS
      CCDS50697.1
      UniProtKB/Swiss-Prot
      A2AR82, Q9D518
      Related
      ENSMUSP00000106076.3, ENSMUST00000110446.9
      Conserved Domains (1) summary
      pfam14922
      Location:143293
      FWWh; Protein of unknown function

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      125825403..125994048 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500348.5XP_006500411.1  protein FAM227B isoform X1

      Conserved Domains (1) summary
      pfam14922
      Location:213358
      FWWh; Protein of unknown function
    2. XM_006500349.3XP_006500412.1  protein FAM227B isoform X2

      Conserved Domains (1) summary
      pfam14922
      Location:51196
      FWWh; Protein of unknown function
    3. XM_006500350.3XP_006500413.1  protein FAM227B isoform X3

      Conserved Domains (1) summary
      pfam14922
      Location:19164
      FWWh; Protein of unknown function