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    Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310399, updated on 2-Nov-2024

    Summary

    Official Symbol
    Naa15provided by RGD
    Official Full Name
    N(alpha)-acetyltransferase 15, NatA auxiliary subunitprovided by RGD
    Primary source
    RGD:1310984
    See related
    EnsemblRapid:ENSRNOG00000012385 AllianceGenome:RGD:1310984
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Narg1
    Summary
    Predicted to enable N-acetyltransferase activity and acetyltransferase activator activity. Predicted to contribute to acetyltransferase activity and ribosome binding activity. Predicted to be involved in several processes, including N-terminal protein amino acid acetylation; positive regulation of DNA-templated transcription; and protein stabilization. Predicted to be located in cytosol and nuclear body. Predicted to be part of NatA complex and transcription regulator complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 50. Orthologous to human NAA15 (N-alpha-acetyltransferase 15, NatA auxiliary subunit). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Muscle (RPKM 210.2), Heart (RPKM 190.2) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Naa15 in Genome Data Viewer
    Location:
    2q26
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (137608883..137671618)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (135458018..135520756)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (140471437..140534259)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485908 Neighboring gene NADH:ubiquinone oxidoreductase subunit C1 Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene RAB33B, member RAS oncogene family Neighboring gene SET domain containing 7, histone lysine methyltransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acetyltransferase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    contributes_to acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal protein amino acid acetylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in N-terminal protein amino acid acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of NatA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of NatA complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 15, NatA auxiliary subunit
    Names
    NMDA receptor regulated 1
    NMDA receptor-regulated gene 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107674.1NP_001101144.1  N-alpha-acetyltransferase 15, NatA auxiliary subunit

      See identical proteins and their annotated locations for NP_001101144.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474003
      UniProtKB/TrEMBL
      A0A8I6A145, A6JV67, D3ZD89
      Related
      ENSRNOP00000017379.6, ENSRNOT00000017379.8
      Conserved Domains (3) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam12569
      Location:187698
      NARP1; NMDA receptor-regulated protein 1
      pfam13414
      Location:82145
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      137608883..137671618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)