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    Ttc34 tetratricopeptide repeat domain 34 [ Mus musculus (house mouse) ]

    Gene ID: 242800, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Ttc34provided by MGI
    Official Full Name
    tetratricopeptide repeat domain 34provided by MGI
    Primary source
    MGI:MGI:2445205
    See related
    Ensembl:ENSMUSG00000046637 AllianceGenome:MGI:2445205
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4932418L02; B230396O12Rik
    Summary
    Orthologous to human TTC34 (tetratricopeptide repeat domain 34). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 8.1), ovary adult (RPKM 3.5) and 1 other tissue See more
    Orthologs
    human all
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    Genomic context

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    See Ttc34 in Genome Data Viewer
    Location:
    4 E2; 4 85.47 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (154921871..154951582)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (154837308..154867125)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13110 Neighboring gene STARR-seq mESC enhancer starr_12237 Neighboring gene actin-related protein T2 Neighboring gene VISTA enhancer mm1492 Neighboring gene STARR-seq mESC enhancer starr_12238 Neighboring gene VISTA enhancer mm1088 Neighboring gene VISTA enhancer mm1090 Neighboring gene STARR-positive B cell enhancer ABC_E6294 Neighboring gene STARR-seq mESC enhancer starr_12240 Neighboring gene STARR-positive B cell enhancer ABC_E2734 Neighboring gene predicted gene 13112 Neighboring gene STARR-positive B cell enhancer ABC_E847 Neighboring gene membrane metallo-endopeptidase-like 1 Neighboring gene peroxiredoxin like 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    2. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    tetratricopeptide repeat protein 34
    Names
    TPR repeat protein 34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172878.4 → NP_766466.4  tetratricopeptide repeat protein 34

      Status: VALIDATED

      Source sequence(s)
      AL607032
      Consensus CDS
      CCDS19015.2
      UniProtKB/TrEMBL
      A0A140LHH0
      Related
      ENSMUSP00000146409.2, ENSMUST00000207854.2
      Conserved Domains (2) summary
      TIGR02917
      Location:543 → 920
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:675 → 703
      TPR; TPR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      154921871..154951582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320227.3 → XP_017175716.1  tetratricopeptide repeat protein 34 isoform X1

      Conserved Domains (1) summary
      sd00006
      Location:674 → 704
      TPR; TPR repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C0Q3.2 GenPept UniProtKB/Swiss-Prot:Q8C0Q3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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