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    icd2 isocitrate dehydrogenase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 887016, updated on 6-Oct-2023

    Summary

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    Gene symbol
    icd2
    Gene description
    isocitrate dehydrogenase
    Locus tag
    Rv0066c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (72274..74511, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene transmembrane protein Neighboring gene antitoxin VapB1 Neighboring gene ribonuclease VapC1 Neighboring gene transcriptional regulator Neighboring gene oxidoreductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of isocitrate dehydrogenase 2 (Rv0066c) from Mycobacterium tuberculosis. Hatzopoulos GN, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 Dec 1. PMID 19052369, Free PMC Article
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Isocitrate dehydrogenase 2 (Icd-2, Rv0066c) from Mycobacterium tuberculosis was cloned and heterologously expressed in Escherichia coli.
      Title: Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of isocitrate dehydrogenase 2 (Rv0066c) from Mycobacterium tuberculosis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    isocitrate dehydrogenase
    NP_214580.1
    • Belongs to the monomeric-type family of IDH. Note that in H37Rv

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      72274..74511 complement
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_214580.1 isocitrate dehydrogenase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_214580.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2I7W2G1
      Conserved Domains (1) summary
      pfam03971
      Location:8 → 741
      IDH; Monomeric isocitrate dehydrogenase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    5KVU_A.1
    5KVU_B.1
    5KVU_C.1
    5KVU_D.1

    Gene LinkOut

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