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    Zfp711 zinc finger protein 711 [ Mus musculus (house mouse) ]

    Gene ID: 245595, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Zfp711provided by MGI
    Official Full Name
    zinc finger protein 711provided by MGI
    Primary source
    MGI:MGI:3045342
    See related
    Ensembl:ENSMUSG00000025529 AllianceGenome:MGI:3045342
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf711; 2810409C01Rik; A230078I01Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 97. Orthologous to human ZNF711 (zinc finger protein 711). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in CNS E18 (RPKM 8.3), CNS E14 (RPKM 7.5) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp711 in Genome Data Viewer
    Location:
    X E1; X 48.76 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (111510259..111544767)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (112600526..112635070)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47778 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene RIKEN cDNA 2010106E10 gene Neighboring gene premature ovarian failure 1B Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_47779 Neighboring gene replication factor C (activator 1) 4 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. Kasowitz SD, et al. PLoS Genet, 2018 May. PMID 29799838, Free PMC Article
    2. A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum. Farini D, et al. Cell Rep, 2020 Jun 2. PMID 32492419
    3. Lineage-specific biology revealed by a finished genome assembly of the mouse. Church DM, et al. PLoS Biol, 2009 May 5. PMID 19468303, Free PMC Article
    4. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 711

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001381898.1 → NP_001368827.1  zinc finger protein 711 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL831771
      UniProtKB/Swiss-Prot
      A2ANX9
      UniProtKB/TrEMBL
      E9PUP8
      Conserved Domains (3) summary
      COG5048
      Location:425 → 805
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 412
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    2. NM_001381899.1 → NP_001368828.1  zinc finger protein 711 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL831771
      UniProtKB/Swiss-Prot
      A2ANX9
      UniProtKB/TrEMBL
      F8WGY3
      Conserved Domains (3) summary
      COG5048
      Location:380 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:506 → 526
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 367
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    3. NM_001381900.1 → NP_001368829.1  zinc finger protein 711 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL831771
      UniProtKB/Swiss-Prot
      A2ANX9
      UniProtKB/TrEMBL
      F8WGY3
      Related
      ENSMUSP00000071717.7, ENSMUST00000071814.13
      Conserved Domains (3) summary
      COG5048
      Location:380 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:506 → 526
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 367
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    4. NM_001405551.1 → NP_001392480.1  zinc finger protein 711 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL831771

    5. NM_177747.4 → NP_808415.2  zinc finger protein 711 isoform 1

      See identical proteins and their annotated locations for NP_808415.2

      Status: VALIDATED

      Source sequence(s)
      AL831771
      Consensus CDS
      CCDS41106.1
      UniProtKB/Swiss-Prot
      A2ANX9
      UniProtKB/TrEMBL
      E9PUP8
      Related
      ENSMUSP00000109036.2, ENSMUST00000113409.8
      Conserved Domains (3) summary
      COG5048
      Location:425 → 805
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 412
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      111510259..111544767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161957.1 → XP_036017850.1  zinc finger protein 711 isoform X1

      UniProtKB/Swiss-Prot
      A2ANX9
      UniProtKB/TrEMBL
      E9PUP8
      Conserved Domains (3) summary
      COG5048
      Location:425 → 805
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:551 → 571
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 412
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    2. XM_036161958.1 → XP_036017851.1  zinc finger protein 711 isoform X2

      UniProtKB/Swiss-Prot
      A2ANX9
      UniProtKB/TrEMBL
      F8WGY3
      Conserved Domains (3) summary
      COG5048
      Location:380 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:506 → 526
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:65 → 367
      Zfx_Zfy_act; Zfx / Zfy transcription activation region

    3. XM_036161959.1 → XP_036017852.1  zinc finger protein 711 isoform X4

      Conserved Domains (2) summary
      sd00017
      Location:162 → 182
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam04704
      Location:2 → 23
      Zfx_Zfy_act; Zfx / Zfy transcription activation region
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2ANX9.1 GenPept UniProtKB/Swiss-Prot:A2ANX9

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