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    Pxdc1 PX domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 66895, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Pxdc1provided by MGI
    Official Full Name
    PX domain containing 1provided by MGI
    Primary source
    MGI:MGI:1914145
    See related
    Ensembl:ENSMUSG00000021411 AllianceGenome:MGI:1914145
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1300014I06Rik
    Summary
    Predicted to enable phosphatidylinositol binding activity. Orthologous to human PXDC1 (PX domain containing 1). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Broad expression in lung adult (RPKM 56.2), small intestine adult (RPKM 31.4) and 20 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Pxdc1 in Genome Data Viewer
    Location:
    13 A3.3; 13 14.16 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (34811823..34836664, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (34627840..34652681, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34153 Neighboring gene predicted gene, 40909 Neighboring gene STARR-seq mESC enhancer starr_34154 Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene STARR-seq mESC enhancer starr_34155 Neighboring gene STARR-seq mESC enhancer starr_34156 Neighboring gene STARR-positive B cell enhancer mm9_chr13:34735014-34735315 Neighboring gene STARR-positive B cell enhancer mm9_chr13:34735430-34735730 Neighboring gene predicted gene 15908 Neighboring gene STARR-seq mESC enhancer starr_34157 Neighboring gene family with sequence similarity 50, member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Hein MY, et al. Cell, 2015 Oct 22. PMID 26496610
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    PX domain-containing protein 1
    Names
    PX domain-containing protein C6orf145 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001382845.1 → NP_001369774.1  PX domain-containing protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC124687
      Conserved Domains (1) summary
      cl02563
      Location:45 → 127
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    2. NM_025831.3 → NP_080107.3  PX domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_080107.3

      Status: VALIDATED

      Source sequence(s)
      AC124687, AK005003
      Consensus CDS
      CCDS36632.1
      UniProtKB/Swiss-Prot
      A0PJ93, Q8JZU6, Q9DBE6
      Related
      ENSMUSP00000051246.8, ENSMUST00000053459.15
      Conserved Domains (1) summary
      cl02563
      Location:45 → 127
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    RNA

    1. NR_168613.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124687, BC037079
      Related
      ENSMUST00000021847.15

    2. NR_168618.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124687, AK005003
      Related
      ENSMUST00000125037.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      34811823..34836664 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8JZU6.2 GenPept UniProtKB/Swiss-Prot:Q8JZU6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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