Nrm nurim (nuclear envelope membrane protein) [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nrmprovided by MGI
Official Full Name: nurim (nuclear envelope membrane protein)provided by MGI
Primary source: MGI:MGI:2146855
See related: Ensembl:ENSMUSG00000059791 AllianceGenome:MGI:2146855
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2610307M02Rik
Summary: Predicted to be located in nuclear envelope. Predicted to be active in nuclear membrane. Is expressed in several structures, including brain ventricular layer; cranium; heart; metanephros; and nasal capsule. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human NRM (nurim). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Broad expression in testis adult (RPKM 84.9), spleen adult (RPKM 32.1) and 21 other tissues See more
Orthologs: human all
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Genomic context

Location:: 17 B1; 17 18.72 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (36171987..36176292)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (35860311..35865400)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Study describes Nurim isoform expression during development and correlate these expression patterns with developmental timing and spatial patterns. The reasons for increased expression of the Nurim isoforms were not clear; however, results suggest that increased expression may be involved in cardiac development.
Title: Isoforms of the nuclear envelope protein Nurim are differentially expressed during heart development in mice.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH139928 (e-PCR)
- UniSTS:222012

AI429796 (e-PCR)
- UniSTS:160657

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in nuclear envelope	ISO Inferred from Sequence Orthology more info
located_in nuclear envelope	ISS Inferred from Sequence or Structural Similarity more info
located_in nuclear inner membrane	TAS Traceable Author Statement more info	PubMed
located_in nuclear lamina	TAS Traceable Author Statement more info	PubMed
is_active_in nuclear membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: nurim

Names: nuclear envelope membrane protein; nuclear rim protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.