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    iglon5 IgLON family member 5 [ Danio rerio (zebrafish) ]

    Gene ID: 550472, updated on 2-Nov-2024

    Summary

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    Official Symbol
    iglon5provided by ZNC
    Official Full Name
    IgLON family member 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-297
    See related
    Ensembl:ENSDARG00000022176 AllianceGenome:ZFIN:ZDB-GENE-050417-297
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:110372
    Summary
    Predicted to be located in plasma membrane and side of membrane. Is expressed in central nervous system; head; optic vesicle; and retinal ganglion cell layer. Orthologous to human IGLON5 (IgLON family member 5). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See iglon5 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (50434317..50824469)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (50489746..50960056)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene upstream transcription factor 2, c-fos interacting-like Neighboring gene hepcidin antimicrobial peptide Neighboring gene si:ch73-90p23.1 Neighboring gene free fatty acid receptor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Large-scale screening for novel low-affinity extracellular protein interactions. Bushell KM, et al. Genome Res, 2008 Apr. PMID 18296487, Free PMC Article
    2. The impact of gene expression regulation on evolution of extracellular signaling pathways. Charoensawan V, et al. Mol Cell Proteomics, 2010 Dec. PMID 20935258, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    igLON family member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017775.2 → NP_001017775.2  igLON family member 5 precursor

      See identical proteins and their annotated locations for NP_001017775.2

      Status: PROVISIONAL

      Source sequence(s)
      CU458930
      UniProtKB/TrEMBL
      A0A8M1N5E7, A4JYK9
      Related
      ENSDARP00000154118.1, ENSDART00000193500.1
      Conserved Domains (4) summary
      smart00410
      Location:217 → 298
      IG_like; Immunoglobulin like
      pfam07679
      Location:128 → 207
      I-set; Immunoglobulin I-set domain
      pfam00047
      Location:223 → 296
      ig; Immunoglobulin domain
      cl11960
      Location:35 → 123
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      50434317..50824469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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