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Crystal Structure of an Archaeal Tyrosyl-tRNA Synthetase Bound to Photocaged L-Tyrosine and Its Potential Application to Time-Resolved X-ray Crystallography.
Title: Crystal Structure of an Archaeal Tyrosyl-tRNA Synthetase Bound to Photocaged L-Tyrosine and Its Potential Application to Time-Resolved X-ray Crystallography.
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Discovery, structure and mechanism of a tetraether lipid synthase.
Title: Discovery, structure and mechanism of a tetraether lipid synthase.
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Structure of the ribosomal P stalk base in archaean Methanococcus jannaschii.
Title: Structure of the ribosomal P stalk base in archaean Methanococcus jannaschii.
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crystal structure of an archaeal NCX [NCX]
Title: Key residues controlling bidirectional ion movements in Na(+)/Ca(2+) exchanger.
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N(5) ,N(10) -methylenetetrahydromethanopterin reductase catalyzed methylglyoxal to lactaldehyde using NADPH.[N(5) ,N(10) -methylenetetrahydromethanopterin reductase ]
Title: N(5) ,N(10) -methylenetetrahydromethanopterin reductase from Methanocaldococcus jannaschii also serves as a methylglyoxal reductase.
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Data suggest that sodium ion binding or calcium ion binding to NCX differentially stabilizes the outward-facing and inward-facing conformational states as the protein sits in the cell membrane; these distinctly stabilized ion-occluded states may control ion release dynamics at opposite sides of the cell membrane. [NCX, Na+/Ca2+ exchanger]
Title: Dynamic distinctions in the Na(+)/Ca(2+) exchanger adopting the inward- and outward-facing conformational states.
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MJ0796 protein has nucleotide binding domains and not all the nucleotide binding sites of it nucleotide-binding domains are occupied by ATP. [MJ0796]
Title: Nucleotide dependence of the dimerization of ATP binding cassette nucleotide binding domains.
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The binding of NCKX2 Na(+)/Ca(2+)-K(+) exchanger with potassium and calcium ions is accomplished via Asp 575 and 548, respectively: [NCKX2]
Title: Characterization of the Cation Binding Sites in the NCKX2 Na(+)/Ca(2+)-K(+) Exchanger.
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Na(+)/Ca(2+) exchangers use the Na(+) electrochemical gradient across the plasma membrane to extrude intracellular Ca(2+). This study elucidates their mechanisms of extracellular ion recognition and exchange through a structural analysis of the exchanger from Methanococcus jannaschii (NCX_Mj) bound to Na(+), Ca(2+) or Sr(2+) in various occupancies and in an apo state. [sodium-calcium exchanger]
Title: Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger.
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Together this work illuminates purine salvage in M. jannaschii and the critical role of a cysteine residue in maintaining active site conformation of adenine deaminase. [adenine deaminase ]
Title: Purine salvage in Methanocaldococcus jannaschii: Elucidating the role of a conserved cysteine in adenine deaminase.