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    sf3b2 splicing factor 3b, subunit 2 [ Danio rerio (zebrafish) ]

    Gene ID: 570994, updated on 12-Sep-2024

    Summary

    Official Symbol
    sf3b2provided by ZNC
    Official Full Name
    splicing factor 3b, subunit 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070928-1
    See related
    Ensembl:ENSDARG00000018049 AllianceGenome:ZFIN:ZDB-GENE-070928-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb53c07; wu:fb53c07; wu:fb93b08; zgc:136773
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Is expressed in several structures, including mesenchyme; mesoderm; neural plate; neural rod; and tail bud. Orthologous to human SF3B2 (splicing factor 3b subunit 2). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
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    Genomic context

    See sf3b2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (6756206..6800691)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (6620508..6664991)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496143 Neighboring gene dual specificity phosphatase 19b Neighboring gene calpain 1 Neighboring gene uncharacterized LOC137496090 Neighboring gene protein kinase D4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    splicing factor 3B subunit 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105277.3NP_001098747.1  splicing factor 3B subunit 2

      See identical proteins and their annotated locations for NP_001098747.1

      Status: VALIDATED

      Source sequence(s)
      CABZ01073934, CABZ01073935, EH500931, EH527159
      UniProtKB/TrEMBL
      A0A8M1NFV3, A7YT51, F1QLC5
      Related
      ENSDART00000173130.2
      Conserved Domains (3) summary
      smart00581
      Location:526584
      PSP; proline-rich domain in spliceosome associated proteins
      pfam02037
      Location:1346
      SAP; SAP domain
      pfam04037
      Location:396521
      DUF382; Domain of unknown function (DUF382)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      6756206..6800691
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)