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    LOC579102 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [ Strongylocentrotus purpuratus (purple sea urchin) ]

    Gene ID: 579102, updated on 14-Dec-2023

    Summary

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    Gene symbol
    LOC579102
    Gene description
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Strongylocentrotus purpuratus
    Lineage
    Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
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    Genomic context

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    See LOC579102 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145514.1 (436745..511888, complement)
    Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577170.1 (113675..263858)

    NW_022145514.1Genomic Context describing neighboring genes Neighboring gene borealin Neighboring gene probable ribonuclease ZC3H12C Neighboring gene uncharacterized LOC100889470 Neighboring gene PRELI domain containing protein 3B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of epithelial cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Spur_5.0 Primary Assembly

    Genomic

    1. NW_022145514.1 Reference Spur_5.0 Primary Assembly

      Range
      436745..511888 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030977827.1 → XP_030833687.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

      UniProtKB/TrEMBL
      A0A7M7N4U9

    2. XM_030977840.1 → XP_030833700.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2

      UniProtKB/TrEMBL
      A0A7M7N548
      Conserved Domains (9) summary
      cd00275
      Location:1064 → 1187
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08592
      Location:304 → 451
      PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
      cd09932
      Location:649 → 752
      SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
      cd11825
      Location:780 → 833
      SH3_PLCgamma; Src homology 3 domain of Phospholipase C (PLC) gamma
      cd13362
      Location:23 → 142
      PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
      cd16201
      Location:147 → 292
      EFh_PI-PLCgamma; EF-hand motif found in phosphoinositide phospholipase C gamma isozymes (PI-PLC-gamma)
      pfam00387
      Location:934 → 1045
      PI-PLC-Y; Phosphatidylinositol-specific phospholipase C, Y domain
      cl15255
      Location:533 → 632
      SH2; Src homology 2 (SH2) domain
      cl17171
      Location:474 → 508
      PH-like; Pleckstrin homology-like domain

    3. XM_030977834.1 → XP_030833694.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

      UniProtKB/TrEMBL
      A0A7M7N4U9
      Conserved Domains (9) summary
      cd00275
      Location:1065 → 1188
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08592
      Location:304 → 451
      PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
      cd09932
      Location:650 → 753
      SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
      cd11825
      Location:781 → 834
      SH3_PLCgamma; Src homology 3 domain of Phospholipase C (PLC) gamma
      cd13362
      Location:23 → 142
      PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
      cd16201
      Location:147 → 292
      EFh_PI-PLCgamma; EF-hand motif found in phosphoinositide phospholipase C gamma isozymes (PI-PLC-gamma)
      pfam00387
      Location:935 → 1046
      PI-PLC-Y; Phosphatidylinositol-specific phospholipase C, Y domain
      cl15255
      Location:533 → 632
      SH2; Src homology 2 (SH2) domain
      cl17171
      Location:474 → 508
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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