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    LOC578329 E3 ubiquitin-protein ligase TRIP12 [ Strongylocentrotus purpuratus (purple sea urchin) ]

    Gene ID: 578329, updated on 25-Jan-2024

    Summary

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    Gene symbol
    LOC578329
    Gene description
    E3 ubiquitin-protein ligase TRIP12
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Strongylocentrotus purpuratus
    Lineage
    Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
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    Genomic context

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    See LOC578329 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145597.1 (8774832..8837149)
    Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577215.1 (157486..242071)

    NW_022145597.1Genomic Context describing neighboring genes Neighboring gene lymphotoxin-alpha Neighboring gene integrator complex subunit 6-B Neighboring gene multidrug resistance-associated protein 5 Neighboring gene uncharacterized LOC585285

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase TRIP12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Spur_5.0 Primary Assembly

    Genomic

    1. NW_022145597.1 Reference Spur_5.0 Primary Assembly

      Range
      8774832..8837149
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030981766.1 → XP_030837626.1  E3 ubiquitin-protein ligase TRIP12

      UniProtKB/TrEMBL
      A0A7M7NK33
      Conserved Domains (4) summary
      cd00078
      Location:1872 → 2269
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam02825
      Location:882 → 946
      WWE; WWE domain
      pfam05466
      Location:328 → 520
      BASP1; Brain acid soluble protein 1 (BASP1 protein)
      pfam17461
      Location:93 → 205
      DUF5423; Family of unknown function (DUF5423)
    Nucleotide Protein
    Heading Accession and Version

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