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    Sos Son of sevenless [ Drosophila sechellia ]

    Gene ID: 6611201, updated on 23-May-2024

    Summary

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    Gene symbol
    Sos
    Gene description
    Son of sevenless
    Locus tag
    Dsec_GM15254
    See related
    EnsemblRapid:LOC6611201
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Drosophila sechellia
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    GM15254; GM15254-PA
    Orthologs
    fruit fly all
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    Genomic context

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    See Sos in Genome Data Viewer
    Location:
    chromosome: 2L
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    101 current ASM438219v1 (GCF_004382195.1) 2L NC_045949.1 (13505010..13510952)

    Chromosome 2L - NC_045949.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC6611199 Neighboring gene beta-fibrinogenase brevinase Neighboring gene glutamate decarboxylase-like protein black Neighboring gene DNA polymerase gamma, catalytic subunit tam Neighboring gene Actin-related protein 2/3 complex, subunit 1A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_045949.1 Chromosome 2L Reference ASM438219v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein son of sevenless
    Names
    Dsec\GM15254
    Dsec\GM15254-PA
    dsec_GLEANR_1606

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Drosophila sechellia Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM438219v1

    Genomic

    1. NC_045949.1 Reference ASM438219v1

      Range
      13505010..13510952
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032721077.1 → XP_032576968.1  protein son of sevenless

      UniProtKB/TrEMBL
      B4HXA0
      Related
      XP_032576968.1, XM_032721077.1
      Conserved Domains (6) summary
      smart00229
      Location:636 → 790
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      PHA03247
      Location:1196 → 1501
      PHA03247; large tegument protein UL36; Provisional
      cd00155
      Location:824 → 1061
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00160
      Location:248 → 431
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd01261
      Location:475 → 585
      PH_SOS; Son of Sevenless (SOS) Pleckstrin homology (PH) domain
      pfam00125
      Location:89 → 215
      Histone; Core histone H2A/H2B/H3/H4
    Nucleotide Protein Strain
    Heading Accession and Version

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