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    JAZ3 jasmonate-zim-domain protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821055, updated on 18-Sep-2024

    Summary

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    Official Symbol
    JAZ3
    Official Full Name
    jasmonate-zim-domain protein 3
    Primary source
    TAIR:AT3G17860
    Locus tag
    AT3G17860
    See related
    Araport:AT3G17860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    JAI3; JASMONATE-INSENSITIVE 3; jasmonate-zim-domain protein 3; TIFY6B
    Summary
    JAZs are direct targets of the SCFCOI1 E3 ubiquitin-ligase and JA treatment induces their proteasome-mediated degradation. Furthermore, JAI3 negatively regulates the key transcriptional activator of JA responses, AtMYC2. The C-terminal portion of JAZ3, including the Jas domain, appears to be important for JAZ3-COI1 binding in the presence of coronatine.
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    Genomic context

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    See JAZ3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (6119707..6123044)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene ncRNA Neighboring gene tetraticopeptide domain-containing thioredoxin Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BBX24 Interacts with JAZ3 to Promote Growth by Reducing DELLA Activity in Shade Avoidance. Saura-Sánchez M, et al. Plant Cell Physiol, 2023 May 15. PMID 36715091
    2. FILAMENTOUS FLOWER Is a Direct Target of JAZ3 and Modulates Responses to Jasmonate. Boter M, et al. Plant Cell, 2015 Nov. PMID 26530088, Free PMC Article
    3. The JAZ family of repressors is the missing link in jasmonate signalling. Chini A, et al. Nature, 2007 Aug 9. PMID 17637675
    4. A critical role of two positively charged amino acids in the Jas motif of Arabidopsis JAZ proteins in mediating coronatine- and jasmonoyl isoleucine-dependent interactions with the COI1 F-box protein. Melotto M, et al. Plant J, 2008 Sep. PMID 18547396, Free PMC Article
    5. Alternative splicing expands the repertoire of dominant JAZ repressors of jasmonate signaling. Chung HS, et al. Plant J, 2010 Aug. PMID 20525008, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BBX24 Interacts with JAZ3 to Promote Growth by Reducing DELLA Activity in Shade Avoidance.
      Title: BBX24 Interacts with JAZ3 to Promote Growth by Reducing DELLA Activity in Shade Avoidance.
    2. JAZ3 interacts with YABs to attenuate their transcriptional function.
      Title: FILAMENTOUS FLOWER Is a Direct Target of JAZ3 and Modulates Responses to Jasmonate.
    3. The Jas motif mediates the hormone-dependent interaction between JAZ3 and COI1, and between JAZ3 and MYC2.
      Title: The ZIM domain mediates homo- and heteromeric interactions between Arabidopsis JAZ proteins.
    4. JAI3 and other JAZs are direct targets of the SCF(COI1) E3 ubiquitin ligase and jasmonate treatment induces their proteasome degradation [JAI3] [JAZ3]
      Title: The JAZ family of repressors is the missing link in jasmonate signalling.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084705.3
    NM_112667.4
    NM_202601.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within jasmonic acid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    jasmonate-zim-domain protein 3
    NP_001078174.1
    • jasmonate-zim-domain protein 3 (JAZ3); FUNCTIONS IN: protein binding; INVOLVED IN: jasmonic acid mediated signaling pathway; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tify (InterPro:IPR010399), CCT domain-like (InterPro:IPR018467); BEST Arabidopsis thaliana protein match is: jasmonate-zim-domain protein 4 (TAIR:AT1G48500.1); Has 405 Blast hits to 373 proteins in 31 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 0; Plants - 362; Viruses - 0; Other Eukaryotes - 42 (source: NCBI BLink).
    NP_566590.1
    • jasmonate-zim-domain protein 3 (JAZ3); CONTAINS InterPro DOMAIN/s: Tify (InterPro:IPR010399), CCT domain-like (InterPro:IPR018467); BEST Arabidopsis thaliana protein match is: jasmonate-zim-domain protein 4 (TAIR:AT1G48500.1); Has 657 Blast hits to 387 proteins in 36 species: Archae - 0; Bacteria - 0; Metazoa - 2; Fungi - 0; Plants - 365; Viruses - 0; Other Eukaryotes - 290 (source: NCBI BLink).
    NP_974330.1
    • jasmonate-zim-domain protein 3 (JAZ3); CONTAINS InterPro DOMAIN/s: Tify (InterPro:IPR010399), CCT domain-like (InterPro:IPR018467); BEST Arabidopsis thaliana protein match is: jasmonate-zim-domain protein 4 (TAIR:AT1G48500.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6119707..6123044
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338310.1 → NP_001327107.1  jasmonate-zim-domain protein 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VKC1, A0A7G2EQS9, F4J6F9
      Conserved Domains (2) summary
      pfam06200
      Location:142 → 173
      tify; tify domain
      pfam09425
      Location:269 → 293
      CCT_2; Divergent CCT motif

    2. NM_112667.4 → NP_566590.1  jasmonate-zim-domain protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566590.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56W78, Q8LF26, Q9LVI4
      UniProtKB/TrEMBL
      A0A5S9XDD0
      Conserved Domains (2) summary
      pfam06200
      Location:175 → 206
      tify; tify domain
      pfam09425
      Location:302 → 326
      CCT_2; Divergent CCT motif

    3. NM_202601.3 → NP_974330.1  jasmonate-zim-domain protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974330.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VKC1, A8MR24
      Conserved Domains (2) summary
      pfam06200
      Location:162 → 193
      tify; tify domain
      pfam09425
      Location:289 → 313
      CCT_2; Divergent CCT motif

    4. NM_001084705.3 → NP_001078174.1  jasmonate-zim-domain protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078174.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VKC1, A0A7G2EQS9, F4J6F9
      Conserved Domains (2) summary
      pfam06200
      Location:142 → 173
      tify; tify domain
      pfam09425
      Location:269 → 293
      CCT_2; Divergent CCT motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LVI4.1

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