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    2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820473, updated on 18-Sep-2024

    Summary

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    Official Full Name
    2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein
    Primary source
    TAIR:AT3G12900
    Locus tag
    AT3G12900
    See related
    Araport:AT3G12900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (4104463..4106341)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily protein Neighboring gene activator of spomin::LUC2 Neighboring gene NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Neighboring gene miscRNA Neighboring gene Ribosomal protein S5/Elongation factor G/III/V family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Scopoletin 8-Hydroxylase-Mediated Fraxetin Production Is Crucial for Iron Mobilization. Tsai HH, et al. Plant Physiol, 2018 May. PMID 29559590, Free PMC Article
    2. Scopoletin 8-hydroxylase: a novel enzyme involved in coumarin biosynthesis and iron-deficiency responses in Arabidopsis. Siwinska J, et al. J Exp Bot, 2018 Mar 24. PMID 29361149, Free PMC Article
    3. Biosynthesis of redox-active metabolites in response to iron deficiency in plants. Rajniak J, et al. Nat Chem Biol, 2018 May. PMID 29581584, Free PMC Article
    4. A major role of coumarin-dependent ferric iron reduction in strategy I-type iron acquisition in Arabidopsis. Paffrath V, et al. Plant Cell, 2024 Feb 26. PMID 38016103, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_112126.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 2-oxoglutarate-dependent dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables scopoletin 8-hydroxylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within coumarin biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within coumarin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within fraxetin biosynthesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to acidic pH IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to iron ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein
    NP_187896.1
    • 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein; FUNCTIONS IN: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: root; CONTAINS InterPro DOMAIN/s: Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein (TAIR:AT1G55290.1); Has 8653 Blast hits to 8615 proteins in 1001 species: Archae - 0; Bacteria - 1126; Metazoa - 119; Fungi - 1049; Plants - 4930; Viruses - 0; Other Eukaryotes - 1429 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4104463..4106341
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112126.2 → NP_187896.1  2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187896.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178VF14, A0MEV7, Q9LE86
      UniProtKB/TrEMBL
      A0A384KU43, A0A5S9XBI3
      Conserved Domains (1) summary
      PLN02947
      Location:20 → 330
      PLN02947; oxidoreductase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LE86.1

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