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    P-loop containing nucleoside triphosphate hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817411, updated on 18-Sep-2024

    Summary

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    Official Full Name
    P-loop containing nucleoside triphosphate hydrolases superfamily protein
    Primary source
    TAIR:AT2G28620
    Locus tag
    AT2G28620
    See related
    Araport:AT2G28620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T8O18.9; T8O18_9
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    21
    Sequence:
    Chromosome: 2; NC_003071.7 (12264928..12270763, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Homeodomain-like superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Genetic Screen for Mutations Affecting Cell Division in the Arabidopsis thaliana Embryo Identifies Seven Loci Required for Cytokinesis. Gillmor CS, et al. PLoS One, 2016. PMID 26745275, Free PMC Article
    2. A conserved role for kinesin-5 in plant mitosis. Bannigan A, et al. J Cell Sci, 2007 Aug 15. PMID 17652157
    3. Mutant alleles of Arabidopsis RADIALLY SWOLLEN 4 and 7 reduce growth anisotropy without altering the transverse orientation of cortical microtubules or cellulose microfibrils. Wiedemeier AM, et al. Development, 2002 Oct. PMID 12361973
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_128423.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cortical microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinesis by cell plate formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in microtubule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    P-loop containing nucleoside triphosphate hydrolases superfamily protein
    NP_180430.2
    • P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: microtubule motor activity, ATP binding; INVOLVED IN: microtubule-based movement; LOCATED IN: chloroplast; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT3G45850.2); Has 49289 Blast hits to 35260 proteins in 1950 species: Archae - 481; Bacteria - 7561; Metazoa - 22029; Fungi - 4505; Plants - 3473; Viruses - 125; Other Eukaryotes - 11115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12264928..12270763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336181.1 → NP_001323773.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VZA1, A0A1P8AY44, A0A384L023
      Conserved Domains (3) summary
      COG1196
      Location:385 → 634
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd01364
      Location:48 → 401
      KISc_BimC_Eg5; Kinesin motor domain, BimC/Eg5 spindle pole proteins
      NF033916
      Location:485 → 828
      antiphage_ZorA_3; anti-phage defense ZorAB system ZorA

    2. NM_001336182.1 → NP_001323772.1  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VZA1, A0A1P8AY44, A0A384L023
      Conserved Domains (3) summary
      COG1196
      Location:385 → 634
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd01364
      Location:48 → 401
      KISc_BimC_Eg5; Kinesin motor domain, BimC/Eg5 spindle pole proteins
      NF033916
      Location:485 → 828
      antiphage_ZorA_3; anti-phage defense ZorAB system ZorA

    3. NM_128423.2 → NP_180430.2  P-loop containing nucleoside triphosphate hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180430.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IIS5, Q9SIB3
      Conserved Domains (2) summary
      cd01364
      Location:48 → 401
      KISc_BimC_Eg5; Kinesin motor domain, BimC/Eg5 spindle pole proteins
      pfam00225
      Location:56 → 392
      Kinesin; Kinesin motor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4IIS5.1

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