U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    GA2OX8 gibberellin 2-oxidase 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827868, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GA2OX8
    Official Full Name
    gibberellin 2-oxidase 8
    Primary source
    TAIR:AT4G21200
    Locus tag
    AT4G21200
    See related
    Araport:AT4G21200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA GIBBERELLIN 2-OXIDASE 8; ATGA2OX8; F7J7.140; F7J7_140; gibberellin 2-oxidase 8
    Summary
    Encodes a protein with gibberellin 2-oxidase activity which acts specifically on C-20 gibberellins.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GA2OX8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (11302682..11306770)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene DnaJ / Sec63 Brl domains-containing protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene Cytochrome c oxidase biogenesis protein Cmc1-like protein Neighboring gene PPDK regulatory protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A study of gibberellin homeostasis and cryptochrome-mediated blue light inhibition of hypocotyl elongation. Zhao X, et al. Plant Physiol, 2007 Sep. PMID 17644628, Free PMC Article
    2. Overexpression of a novel class of gibberellin 2-oxidases decreases gibberellin levels and creates dwarf plants. Schomburg FM, et al. Plant Cell, 2003 Jan. PMID 12509528, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. scc7-D (suppressors of cry1cry2)is a gain-of-expression allele of the GA2ox8 gene.
      Title: A study of gibberellin homeostasis and cryptochrome-mediated blue light inhibition of hypocotyl elongation.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    NM_001160789.1
    NM_001341476.1
    NM_118239.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables C-19 gibberellin 2-beta-dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables C-20 gibberellin 2-beta-dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gibberellin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gibberellin metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    gibberellin 2-oxidase 8
    NP_001154261.1
    • gibberellin 2-oxidase 8 (GA2OX8); FUNCTIONS IN: C-20 gibberellin 2-beta-dioxygenase activity; INVOLVED IN: gibberellin metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, flower; EXPRESSED DURING: petal differentiation and expansion stage; BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 7 (TAIR:AT1G50960.1); Has 2321 Blast hits to 2310 proteins in 244 species: Archae - 0; Bacteria - 75; Metazoa - 4; Fungi - 39; Plants - 2120; Viruses - 0; Other Eukaryotes - 83 (source: NCBI BLink).
    NP_001320018.1
    • gibberellin 2-oxidase 8 (GA2OX8); FUNCTIONS IN: C-20 gibberellin 2-beta-dioxygenase activity; INVOLVED IN: gibberellin metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, flower; EXPRESSED DURING: petal differentiation and expansion stage; BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 7 (TAIR:AT1G50960.1); Has 2972 Blast hits to 2961 proteins in 383 species: Archae - 0; Bacteria - 137; Metazoa - 2; Fungi - 57; Plants - 2676; Viruses - 0; Other Eukaryotes - 100 (source: NCBI BLink).
    NP_193852.2
    • gibberellin 2-oxidase 8 (GA2OX8); CONTAINS InterPro DOMAIN/s: Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 7 (TAIR:AT1G50960.1); Has 8586 Blast hits to 8547 proteins in 1007 species: Archae - 0; Bacteria - 1133; Metazoa - 115; Fungi - 1020; Plants - 4926; Viruses - 0; Other Eukaryotes - 1392 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11302682..11306770
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118239.3 → NP_193852.2  gibberellin 2-oxidase 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193852.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MF87, O49561, Q1PE62
      UniProtKB/TrEMBL
      A0A178UVM9, A0A5S9XUE7, A0A654FRC1
      Conserved Domains (3) summary
      PLN02403
      Location:40 → 333
      PLN02403; aminocyclopropanecarboxylate oxidase
      pfam03171
      Location:186 → 290
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
      pfam14226
      Location:42 → 137
      DIOX_N; non-haem dioxygenase in morphine synthesis N-terminal

    2. NM_001341476.1 → NP_001320018.1  gibberellin 2-oxidase 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UUC9, F4JIN8

    3. NM_001160789.1 → NP_001154261.1  gibberellin 2-oxidase 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154261.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UUC9, F4JIN9
      Conserved Domains (1) summary
      pfam14226
      Location:42 → 105
      DIOX_N; non-haem dioxygenase in morphine synthesis N-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49561.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.