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    AHG1 Protein phosphatase 2C family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835250, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AHG1
    Official Full Name
    Protein phosphatase 2C family protein
    Primary source
    TAIR:AT5G51760
    Locus tag
    AT5G51760
    See related
    Araport:AT5G51760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABA-hypersensitive germination 1; MIO24.11; MIO24_11
    Summary
    Encodes AHG1 (ABA-hypersensitive germination 1), a putative protein phosphatase 2C (PP2C). Expressed in seeds. AHG1 functions in seed development and germination.
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    Genomic context

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    See AHG1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (21026805..21029188)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene subtilase 1.3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ABA-Hypersensitive Germination1 encodes a protein phosphatase 2C, an essential component of abscisic acid signaling in Arabidopsis seed. Nishimura N, et al. Plant J, 2007 Jun. PMID 17461784
    2. Control of seed dormancy and germination by DOG1-AHG1 PP2C phosphatase complex via binding to heme. Nishimura N, et al. Nat Commun, 2018 Jun 6. PMID 29875377, Free PMC Article
    3. Release of GTP Exchange Factor Mediated Down-Regulation of Abscisic Acid Signal Transduction through ABA-Induced Rapid Degradation of RopGEFs. Li Z, et al. PLoS Biol, 2016 May. PMID 27192441, Free PMC Article
    4. Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis. Umezawa T, et al. Proc Natl Acad Sci U S A, 2009 Oct 13. PMID 19805022, Free PMC Article
    5. Direct interactions of ABA-insensitive(ABI)-clade protein phosphatase(PP)2Cs with calcium-dependent protein kinases and ABA response element-binding bZIPs may contribute to turning off ABA response. Lynch T, et al. Plant Mol Biol, 2012 Dec. PMID 23007729

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that that ABA HYPERSENSITIVE GERMINATION1 (AHG1) interacts with DELAY OF GERMINATION1 (DOG1), which is a pivotal positive regulator in seed dormancy.
      Title: Control of seed dormancy and germination by DOG1-AHG1 PP2C phosphatase complex via binding to heme.
    2. Mutants showed hypersensitivity to ABA, NaCl, KCl, mannitol, glucose and sucrose during germination and post-germination growth, but did not display any significant phenotypes in adult plants.
      Title: ABA-Hypersensitive Germination1 encodes a protein phosphatase 2C, an essential component of abscisic acid signaling in Arabidopsis seed.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_124555.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Protein phosphatase 2C family protein
    NP_199989.1
    • ABA-hypersensitive germination 1 (AHG1); FUNCTIONS IN: protein serine/threonine phosphatase activity, catalytic activity; INVOLVED IN: seed germination, response to abscisic acid stimulus, seed development; LOCATED IN: protein serine/threonine phosphatase complex; EXPRESSED IN: seed; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C, manganese/magnesium aspartate binding site (InterPro:IPR000222), Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: highly ABA-induced PP2C gene 3 (TAIR:AT2G29380.1); Has 6503 Blast hits to 6478 proteins in 370 species: Archae - 6; Bacteria - 133; Metazoa - 1626; Fungi - 786; Plants - 2672; Viruses - 7; Other Eukaryotes - 1273 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21026805..21029188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344957.1 → NP_001331276.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BDH5, A0A7G2FHF5

    2. NM_124555.3 → NP_199989.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199989.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FLI3
      UniProtKB/TrEMBL
      A0A654GAC6, A0A7G2FHF5
      Conserved Domains (1) summary
      cd00143
      Location:109 → 411
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FLI3.1

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