Major facilitator superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: Major facilitator superfamily protein
Primary source: TAIR:AT1G22550
Locus tag: AT1G22550
See related: Araport:AT1G22550
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F12K8.11; F12K8_11
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 4

Sequence:: Chromosome: 1; NC_003070.9 (7966500..7968692, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

At1g22550 (NPF5.16) is involved in the nitrate from vacuoles into cytosol, thus serving as important player to modulate nitrate allocation between roots and shoots.
Title: Tonoplast-localized nitrate uptake transporters involved in vacuolar nitrate efflux and reallocation in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_102104.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables dipeptide transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables low-affinity nitrate transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables tripeptide transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within nitrate transmembrane transport	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in plant-type vacuole membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Major facilitator superfamily protein

NP_173671.1

Major facilitator superfamily protein; FUNCTIONS IN: transporter activity; INVOLVED IN: oligopeptide transport; LOCATED IN: membrane; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: PTR2 family proton/oligopeptide symporter, conserved site (InterPro:IPR018456), Oligopeptide transporter (InterPro:IPR000109), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major facilitator superfamily protein (TAIR:AT1G22570.1); Has 7743 Blast hits to 7641 proteins in 1463 species: Archae - 0; Bacteria - 4037; Metazoa - 494; Fungi - 461; Plants - 2187; Viruses - 0; Other Eukaryotes - 564 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

7966500..7968692 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_102104.4 → NP_173671.1 Major facilitator superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_173671.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q84VX2, Q9SK96

UniProtKB/TrEMBL

A0A178WGZ5, A0A5S9VJD9

Conserved Domains (1) summary

cl21472
Location:141 → 522

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...