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    ERF12 ERF domain protein 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839732, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ERF12
    Official Full Name
    ERF domain protein 12
    Primary source
    TAIR:AT1G28360
    Locus tag
    AT1G28360
    See related
    Araport:AT1G28360
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATERF12; ERF domain protein 12; ERF DOMAIN PROTEIN 12; F3M18.21; F3M18_21
    Summary
    encodes a member of the ERF (ethylene response factor) subfamily B-1 of ERF/AP2 transcription factor family (ERF12). The protein contains one AP2 domain. There are 15 members in this subfamily including ATERF-3, ATERF-4, ATERF-7, and leafy petiole.
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    Genomic context

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    See ERF12 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (9951762..9953105)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene receptor like protein 4 Neighboring gene Nucleotidylyl transferase superfamily protein Neighboring gene ERF domain protein 11 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A phylogenetically conserved APETALA2/ETHYLENE RESPONSE FACTOR, ERF12, regulates Arabidopsis floral development. Chandler JW, et al. Plant Mol Biol, 2020 Jan. PMID 31807981, Free PMC Article
    2. Repression domains of class II ERF transcriptional repressors share an essential motif for active repression. Ohta M, et al. Plant Cell, 2001 Aug. PMID 11487705, Free PMC Article
    3. The AP2/EREBP family of plant transcription factors. Riechmann JL, et al. Biol Chem, 1998 Jun. PMID 9687012
    4. The TOPLESS interactome: a framework for gene repression in Arabidopsis. Causier B, et al. Plant Physiol, 2012 Jan. PMID 22065421, Free PMC Article
    5. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A phylogenetically conserved APETALA2/ETHYLENE RESPONSE FACTOR, ERF12, regulates Arabidopsis floral development.
      Title: A phylogenetically conserved APETALA2/ETHYLENE RESPONSE FACTOR, ERF12, regulates Arabidopsis floral development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_102602.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ERF domain protein 12
    NP_174158.1
    • ERF domain protein 12 (ERF12); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: ethylene responsive element binding factor 4 (TAIR:AT3G15210.1); Has 5550 Blast hits to 5447 proteins in 245 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 0; Plants - 5541; Viruses - 0; Other Eukaryotes - 8 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9951762..9953105
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102602.6 → NP_174158.1  ERF domain protein 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174158.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94ID6, Q9SGN3
      UniProtKB/TrEMBL
      A0A178WCW0, A0A5S9W9D3, A0A7G2DWK9
      Conserved Domains (1) summary
      smart00380
      Location:11 → 68
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94ID6.1

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