U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    BLH8 BEL1-like homeodomain 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817343, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    BLH8
    Official Full Name
    BEL1-like homeodomain 8
    Primary source
    TAIR:AT2G27990
    Locus tag
    AT2G27990
    See related
    Araport:AT2G27990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BEL1-like homeodomain 8; PNF; POUND-FOOLISH; T1E2.9; T1E2_9
    Summary
    Encodes a BEL1-like homeobox gene that functions together with PNY in meristem maintenance by regulating the allocation process during vegetative and reproductive development. Both gene products are required for the competence of the SAM to respond properly to floral inductive signals.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See BLH8 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (11921350..11924748, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene cyclin-dependent kinase-subunit 1 Neighboring gene Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein Neighboring gene CDK-subunit 2 Neighboring gene chaperonin-60alpha Neighboring gene Eukaryotic aspartyl protease family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Khan M, et al. Plant Physiol, 2015 Nov. PMID 26417006, Free PMC Article
    2. Regulation of shoot meristem integrity during Arabidopsis vegetative development. Ung N, et al. Plant Signal Behav, 2011 Aug. PMID 21822063, Free PMC Article
    3. Regulation of the SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE genes/microRNA156 module by the homeodomain proteins PENNYWISE and POUND-FOOLISH in Arabidopsis. Lal S, et al. Mol Plant, 2011 Nov. PMID 21653282
    4. The role of PENNYWISE and POUND-FOOLISH in the maintenance of the shoot apical meristem in Arabidopsis. Ung N, et al. Plant Physiol, 2011 Jun. PMID 21505100, Free PMC Article
    5. A novel role of BELL1-like homeobox genes, PENNYWISE and POUND-FOOLISH, in floral patterning. Yu L, et al. Planta, 2009 Feb. PMID 19082619

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The data reveal a potential mechanism by which repression of lateral organ boundary genes by PNY-PNF is essential for flowering.
      Title: Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    2. Regulation of meristem central zone integrity by PNY and PNF is crucial for vegetative and reproductive development.
      Title: Regulation of shoot meristem integrity during Arabidopsis vegetative development.
    3. SPL3, SPL4, and SPL5 function is dependent upon PNY and PNF
      Title: Regulation of the SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE genes/microRNA156 module by the homeodomain proteins PENNYWISE and POUND-FOOLISH in Arabidopsis.
    4. PNY and PNF act to restrict organogenesis to the peripheral zone by maintaining a boundary between the central zone and peripheral zone.
      Title: The role of PENNYWISE and POUND-FOOLISH in the maintenance of the shoot apical meristem in Arabidopsis.
    5. PNF functions in the inner whorls to regulate flower patterning events. [PNF]
      Title: A novel role of BELL1-like homeobox genes, PENNYWISE and POUND-FOOLISH, in floral patterning.
    6. combined lesions in ATH1, PNY and PNF result in a full phenocopy of shoot apical meristem loss-of-function mutants.
      Title: Shoot apical meristem function in Arabidopsis requires the combined activities of three BEL1-like homeodomain proteins.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001336138.1
    NM_128358.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within inflorescence development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within internode patterning IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within maintenance of floral meristem identity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within maintenance of inflorescence meristem identity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pattern specification process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within plant organ formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within secondary shoot formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    BEL1-like homeodomain 8
    NP_180366.1
    • BEL1-like homeodomain 8 (BLH8); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), POX (InterPro:IPR006563), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: POX (plant homeobox) family protein (TAIR:AT5G02030.1); Has 5076 Blast hits to 5073 proteins in 336 species: Archae - 0; Bacteria - 0; Metazoa - 2093; Fungi - 319; Plants - 2481; Viruses - 0; Other Eukaryotes - 183 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11921350..11924748 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128358.3 → NP_180366.1  BEL1-like homeodomain 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180366.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SJJ3
      UniProtKB/TrEMBL
      A0A178VN67, A0A5S9X1V0, A0A654EYE0
      Conserved Domains (2) summary
      smart00574
      Location:257 → 385
      POX; domain associated with HOX domains
      pfam05920
      Location:442 → 481
      Homeobox_KN; Homeobox KN domain

    2. NM_001336138.1 → NP_001324957.1  BEL1-like homeodomain 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B1P7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJJ3.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.