NRPD4 RNA polymerase II, Rpb4, core protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: NRPD4
Official Full Name: RNA polymerase II, Rpb4, core protein
Primary source: TAIR:AT4G15950
Locus tag: AT4G15950
See related: Araport:AT4G15950
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DL4012W; FCAALL.240; NRPE4; RDM2; RNA-DIRECTED DNA METHYLATION 2
Summary: Non-catalytic subunit common to Nuclear DNA-dependent RNA polymerases IV and V; homologous to budding yeast RPB4. Role in gene silencing. Required for RNA-directed DNA methylation.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_117687.2

Function	Evidence Code	Pubs
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription initiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within siRNA processing	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
part_of RNA polymerase IV complex	IDA Inferred from Direct Assay more info	PubMed
part_of RNA polymerase IV complex	IPI Inferred from Physical Interaction more info	PubMed
part_of RNA polymerase V complex	IDA Inferred from Direct Assay more info	PubMed
part_of RNA polymerase V complex	IPI Inferred from Physical Interaction more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_193330.3

NRPD4; FUNCTIONS IN: DNA-directed RNA polymerase activity, nucleotide binding, catalytic activity; INVOLVED IN: RNA interference, interphase, production of siRNA involved in RNA interference, DNA methylation on cytosine within a CHH sequence; LOCATED IN: DNA-directed RNA polymerase V complex, nucleus, DNA-directed RNA polymerase IV complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: HRDC-like (InterPro:IPR010997), RNA polymerase II, Rpb4 (InterPro:IPR005574), RNA polymerase II, Rpb4, core (InterPro:IPR006590); BEST Arabidopsis thaliana protein match is: RNA polymerase II, Rpb4, core protein (TAIR:AT5G09920.1); Has 23 Blast hits to 23 proteins in 3 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 23; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).