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    MAPKKK16 mitogen-activated protein kinase kinase kinase 16 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828796, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MAPKKK16
    Official Full Name
    mitogen-activated protein kinase kinase kinase 16
    Primary source
    TAIR:AT4G26890
    Locus tag
    AT4G26890
    See related
    Araport:AT4G26890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10M23.230; F10M23_230; mitogen-activated protein kinase kinase kinase 16
    Summary
    member of MEKK subfamily
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    Genomic context

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    See MAPKKK16 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (13511837..13513406)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Stigma-specific Stig1 family protein Neighboring gene ncRNA Neighboring gene HIS HF Neighboring gene Dihydrolipoamide succinyltransferase Neighboring gene START (StAR-related lipid-transfer) lipid-binding domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis MAP3K16 and Other Salt-Inducible MAP3Ks Regulate ABA Response Redundantly. Choi SW, et al. Mol Cells, 2017 Mar. PMID 28292003, Free PMC Article
    2. Wounding and Insect Feeding Trigger Two Independent MAPK Pathways with Distinct Regulation and Kinetics. Sözen C, et al. Plant Cell, 2020 Jun. PMID 32265268, Free PMC Article
    3. Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. Nemoto K, et al. Phytochemistry, 2011 Jul. PMID 21477822
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_118823.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 16
    NP_194419.2
    • mitogen-activated protein kinase kinase kinase 16 (MAPKKK16); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: root, carpel; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: mitogen-activated protein kinase kinase kinase 15 (TAIR:AT5G55090.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13511837..13513406
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118823.4 → NP_194419.2  mitogen-activated protein kinase kinase kinase 16 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194419.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V0J2, F4JVS7, Q9SZ29
      Conserved Domains (1) summary
      cd06606
      Location:4 → 253
      STKc_MAPKKK; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase
    Nucleotide Protein
    Heading Accession and Version

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