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    TIP1 Ankyrin repeat family protein with DHHC zinc finger domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832157, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIP1
    Official Full Name
    Ankyrin repeat family protein with DHHC zinc finger domain-containing protein
    Primary source
    TAIR:AT5G20350
    Locus tag
    AT5G20350
    See related
    Araport:AT5G20350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5O24.240; F5O24_240; TIP GROWTH DEFECTIVE 1
    Summary
    Encodes a protein containing ankyrin and DHHC-CRD domain. Acts to restrict the size of the swelling that forms at the beginning of root hair cell growth, possibly by a mechanism that requires RHD1. Mutant displays defects in both root hair and pollen tube growth.
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    Genomic context

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    See TIP1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Sequence:
    Chromosome: 5; NC_003076.8 (6876441..6881506)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene beta-1,3-glucanase 4 Neighboring gene beta-1,3-glucanase 5 Neighboring gene Octicosapeptide/Phox/Bem1p (PB1) domain-containing protein / tetratricopeptide repeat (TPR)-containing protein Neighboring gene serine-rich protein-like protein Neighboring gene phosphate transporter 4;5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pollen tube and root-hair tip growth is disrupted in a mutant of Arabidopsis thaliana. Schiefelbein J, et al. Plant Physiol, 1993 Nov. PMID 8022944, Free PMC Article
    2. The TIP GROWTH DEFECTIVE1 S-acyl transferase regulates plant cell growth in Arabidopsis. Hemsley PA, et al. Plant Cell, 2005 Sep. PMID 16100337, Free PMC Article
    3. Tip growth defective1 interacts with cellulose synthase A3 to regulate cellulose biosynthesis in Arabidopsis. Zhang L, et al. Plant Mol Biol, 2022 Sep. PMID 35644016
    4. Label-free protein quantification for plant Golgi protein localization and abundance. Nikolovski N, et al. Plant Physiol, 2014 Oct. PMID 25122472, Free PMC Article
    5. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Tip Growth Defective1 interacts with the cellulose synthase complex to regulate cellulose synthesis in Arabidopsis thaliana.
      Title: Tip Growth Defective1 interacts with the cellulose synthase complex to regulate cellulose synthesis in Arabidopsis thaliana.
    2. Results demonstrate that S-acylation is essential for normal plant cell growth and identify TIP GROWTH DEFECTIVE1 (TIP1), a plant S-acyl transferase.
      Title: The TIP GROWTH DEFECTIVE1 S-acyl transferase regulates plant cell growth in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_122042.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables S-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables S-acyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables acyl binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-cysteine S-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell tip growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cellulose biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of secondary cell wall biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endosome HDA PubMed 
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    Ankyrin repeat family protein with DHHC zinc finger domain-containing protein
    NP_197535.2
    • TIP GROWTH DEFECTIVE 1 (TIP1); FUNCTIONS IN: acyl binding, S-acyltransferase activity; INVOLVED IN: response to salt stress, cell tip growth; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, DHHC-type (InterPro:IPR001594), Ankyrin repeat-containing domain (InterPro:IPR020683), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: Ankyrin repeat family protein with DHHC zinc finger domain (TAIR:AT2G14255.1); Has 74376 Blast hits to 32836 proteins in 1312 species: Archae - 100; Bacteria - 6632; Metazoa - 35576; Fungi - 7192; Plants - 4422; Viruses - 788; Other Eukaryotes - 19666 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6876441..6881506
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122042.4 → NP_197535.2  Ankyrin repeat family protein with DHHC zinc finger domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197535.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      I1VCB2, Q0WQT8, Q52T38
      UniProtKB/TrEMBL
      A0A5S9Y6A0, A0A654G2X5
      Conserved Domains (4) summary
      PHA03095
      Location:55 → 252
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:64 → 95
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:38 → 128
      Ank_2; Ankyrin repeats (3 copies)
      cl19890
      Location:256 → 506
      DHHC; DHHC palmitoyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q52T38.1

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