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    ADF2 actin depolymerizing factor 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823743, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ADF2
    Official Full Name
    actin depolymerizing factor 2
    Primary source
    TAIR:AT3G46000
    Locus tag
    AT3G46000
    See related
    Araport:AT3G46000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin depolymerizing factor 2
    Summary
    Encodes depolymerizing factor 2.
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    Genomic context

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    See ADF2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (16907334..16909119, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Histone superfamily protein Neighboring gene Cofilin/tropomyosin-type actin-binding protein family Neighboring gene actin depolymerizing factor 1 Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of the pollen-specific actin-depolymerizing factor LlADF1. Allwood EG, et al. Plant Cell, 2002 Nov. PMID 12417710, Free PMC Article
    2. Actin-depolymerizing factor2-mediated actin dynamics are essential for root-knot nematode infection of Arabidopsis. Clément M, et al. Plant Cell, 2009 Sep. PMID 19794115, Free PMC Article
    3. Plant Actin-Depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes throughout Evolution. Nan Q, et al. Plant Cell, 2017 Feb. PMID 28123105, Free PMC Article
    4. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001339232.1
    NM_001339233.1
    NM_114469.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament depolymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin filament depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    actin depolymerizing factor 2
    NP_566882.1
    • actin depolymerizing factor 2 (ADF2); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 4 (TAIR:AT5G59890.1); Has 1494 Blast hits to 1493 proteins in 266 species: Archae - 0; Bacteria - 8; Metazoa - 650; Fungi - 147; Plants - 513; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16907334..16909119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114469.5 → NP_566882.1  actin depolymerizing factor 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566882.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39251, Q9LZT2
      UniProtKB/TrEMBL
      A0A178V7X3, A0A5S9XIC2
      Conserved Domains (1) summary
      cd11286
      Location:6 → 135
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    2. NM_001339232.1 → NP_001327289.1  actin depolymerizing factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LRV3, A0A654FD75
      Conserved Domains (1) summary
      cl15697
      Location:23 → 154
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    3. NM_001339233.1 → NP_001327290.1  actin depolymerizing factor 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z352
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39251.1

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