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    ALATS Alanyl-tRNA synthetase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841442, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ALATS
    Official Full Name
    Alanyl-tRNA synthetase
    Primary source
    TAIR:AT1G50200
    Locus tag
    AT1G50200
    See related
    Araport:AT1G50200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ACD; Alanyl-tRNA synthetase; ALARS; F14I3.17; F14I3_17
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    Genomic context

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    See ALATS in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    23
    Sequence:
    Chromosome: 1; NC_003070.9 (18591194..18598569, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene NB-ARC domain-containing disease resistance protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene miscRNA Neighboring gene B3 domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual targeting is the rule for organellar aminoacyl-tRNA synthetases in Arabidopsis thaliana. Duchêne AM, et al. Proc Natl Acad Sci U S A, 2005 Nov 8. PMID 16251277, Free PMC Article
    2. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001198257.1
    NM_103905.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alanine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Alanyl-tRNA synthetase
    NP_001185186.2
    • Alanyl-tRNA synthetase (ALATS); FUNCTIONS IN: alanine-tRNA ligase activity, ligase activity, forming aminoacyl-tRNA and related compounds, nucleotide binding, ATP binding, nucleic acid binding; INVOLVED IN: alanyl-tRNA aminoacylation; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Alanyl-tRNA synthetase, class IIc (InterPro:IPR002318), Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain (InterPro:IPR018163), Alanyl-tRNA synthetase, class IIc, anti-codon-binding domain (InterPro:IPR018162), Alanyl-tRNA synthetase, class IIc, core domain (InterPro:IPR018165), Threonyl/alanyl tRNA synthetase, SAD (InterPro:IPR012947), Alanyl-tRNA synthetase, class IIc, N-terminal (InterPro:IPR018164), Phosphoesterase, DHHA1 (InterPro:IPR003156); BEST Arabidopsis thaliana protein match is: Alanyl-tRNA synthetase, class IIc (TAIR:AT5G22800.1).
    NP_175439.2
    • Alanyl-tRNA synthetase (ALATS); FUNCTIONS IN: alanine-tRNA ligase activity, ligase activity, forming aminoacyl-tRNA and related compounds, nucleotide binding, nucleic acid binding, ATP binding; INVOLVED IN: alanyl-tRNA aminoacylation, response to cadmium ion; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain (InterPro:IPR018163), Alanyl-tRNA synthetase, class IIc (InterPro:IPR002318), Alanyl-tRNA synthetase, class IIc, anti-codon-binding domain (InterPro:IPR018162), Alanyl-tRNA synthetase, class IIc, core domain (InterPro:IPR018165), Threonyl/alanyl tRNA synthetase, SAD (InterPro:IPR012947), Alanyl-tRNA synthetase, class IIc, N-terminal (InterPro:IPR018164), Phosphoesterase, DHHA1 (InterPro:IPR003156); BEST Arabidopsis thaliana protein match is: Alanyl-tRNA synthetase, class IIc (TAIR:AT5G22800.1); Has 14725 Blast hits to 14601 proteins in 3159 species: Archae - 403; Bacteria - 7275; Metazoa - 708; Fungi - 195; Plants - 148; Viruses - 0; Other Eukaryotes - 5996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18591194..18598569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198257.1 → NP_001185186.2  Alanyl-tRNA synthetase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EHS4, F4I4Z2

    2. NM_103905.4 → NP_175439.2  Alanyl-tRNA synthetase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175439.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04159, P36428, Q8GUG2, Q9SX40
      UniProtKB/TrEMBL
      A0A654EHS4
      Conserved Domains (3) summary
      PLN02900
      Location:49 → 1000
      PLN02900; alanyl-tRNA synthetase
      cd00673
      Location:61 → 307
      AlaRS_core; Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of ...
      cl08469
      Location:571 → 794
      tRNA_SAD; Threonyl and Alanyl tRNA synthetase second additional domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36428.3

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