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    CKX7 cytokinin oxidase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832248, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CKX7
    Official Full Name
    cytokinin oxidase 7
    Primary source
    TAIR:AT5G21482
    Locus tag
    AT5G21482
    See related
    Araport:AT5G21482
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CYTOKININ OXIDASE 5; ATCKX5; cytokinin oxidase 7
    Summary
    This gene used to be called AtCKX5. It encodes a protein whose sequence is similar to cytokinin oxidase/dehydrogenase, which catalyzes the degradation of cytokinins.
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    Genomic context

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    See CKX7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (7226606..7230304)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene tRNA-Asp Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene pseudo Neighboring gene RNI-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of the cytosolic cytokinin oxidase/dehydrogenase (CKX7) from Arabidopsis causes specific changes in root growth and xylem differentiation. Köllmer I, et al. Plant J, 2014 May. PMID 24528491
    2. Vacuolar and cytosolic cytokinin dehydrogenases of Arabidopsis thaliana: heterologous expression, purification and properties. Kowalska M, et al. Phytochemistry, 2010 Dec. PMID 20825956
    3. Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species. Schmülling T, et al. J Plant Res, 2003 Jun. PMID 12721786
    4. Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity. Werner T, et al. Plant Cell, 2003 Nov. PMID 14555694, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CKX7 plays a role in root growth and xylem differentiation.
      Title: Overexpression of the cytosolic cytokinin oxidase/dehydrogenase (CKX7) from Arabidopsis causes specific changes in root growth and xylem differentiation.
    Submit: New GeneRIF Correction

    General gene information

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    NM_180532.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytokinin dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables cytokinin dehydrogenase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinin catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytokinin oxidase 7
    NP_850863.1
    • cytokinin oxidase 7 (CKX7); CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase/dehydrogenase 1 (TAIR:AT2G41510.1); Has 8328 Blast hits to 8321 proteins in 1506 species: Archae - 208; Bacteria - 5322; Metazoa - 141; Fungi - 1495; Plants - 573; Viruses - 0; Other Eukaryotes - 589 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7226606..7230304
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180532.3 → NP_850863.1  cytokinin oxidase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850863.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FUJ1
      UniProtKB/TrEMBL
      A0A178UIC8, A0A5S9Y631
      Conserved Domains (3) summary
      PLN02441
      Location:1 → 523
      PLN02441; cytokinin dehydrogenase
      pfam01565
      Location:62 → 207
      FAD_binding_4; FAD binding domain
      pfam09265
      Location:239 → 520
      Cytokin-bind; Cytokinin dehydrogenase 1, FAD and cytokinin binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FUJ1.1

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