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    LCBK2 Diacylglycerol kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819217, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LCBK2
    Official Full Name
    Diacylglycerol kinase family protein
    Primary source
    TAIR:AT2G46090
    Locus tag
    AT2G46090
    See related
    Araport:AT2G46090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    long-chain base (LCB) kinase 2; T3F17.26
    Summary
    Encodes a putative sphingosine kinase (SphK) containing the five conserved domains (C1-C5) previously identified in SphKs.
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    Genomic context

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    See LCBK2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (18950802..18953275)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 12 Neighboring gene BPS1-like protein Neighboring gene Nuclear transport factor 2 (NTF2) family protein Neighboring gene ketopantoate hydroxymethyltransferase 1 Neighboring gene tRNA-Glu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phytosphingosine-phosphate is a signal for AtMPK6 activation and Arabidopsis response to chilling. Dutilleul C, et al. New Phytol, 2012 Apr. PMID 22236066
    2. Arabidopsis sphingosine kinase and the effects of phytosphingosine-1-phosphate on stomatal aperture. Coursol S, et al. Plant Physiol, 2005 Feb. PMID 15665242, Free PMC Article
    3. The calmodulin-binding protein kinase 3 is part of heat-shock signal transduction in Arabidopsis thaliana. Liu HT, et al. Plant J, 2008 Sep. PMID 18466301
    4. Systematic analysis of protein subcellular localization and interaction using high-throughput transient transformation of Arabidopsis seedlings. Marion J, et al. Plant J, 2008 Oct. PMID 18643979
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_130172.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables D-erythro-sphingosine kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phytosphingosine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Diacylglycerol kinase family protein
    NP_566064.1
    • Diacylglycerol kinase family protein; FUNCTIONS IN: diacylglycerol kinase activity, D-erythro-sphingosine kinase activity; INVOLVED IN: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; LOCATED IN: mitochondrion; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Diacylglycerol kinase, catalytic domain (InterPro:IPR001206), Conserved hypothetical protein CHP00147 (InterPro:IPR005218); BEST Arabidopsis thaliana protein match is: long-chain base (LCB) kinase 1 (TAIR:AT5G23450.2); Has 6078 Blast hits to 6077 proteins in 1657 species: Archae - 15; Bacteria - 4829; Metazoa - 327; Fungi - 124; Plants - 145; Viruses - 0; Other Eukaryotes - 638 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18950802..18953275
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130172.5 → NP_566064.1  Diacylglycerol kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566064.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82359, Q94EZ0
      UniProtKB/TrEMBL
      A0A178VWT6, A0A5S9X7D6, A0A654F2D8
      Conserved Domains (1) summary
      COG1597
      Location:56 → 363
      LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82359.1

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