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    Rdh10 retinol dehydrogenase 10 (all-trans) [ Mus musculus (house mouse) ]

    Gene ID: 98711, updated on 2-Nov-2024

    Summary

    Official Symbol
    Rdh10provided by MGI
    Official Full Name
    retinol dehydrogenase 10 (all-trans)provided by MGI
    Primary source
    MGI:MGI:1924238
    See related
    Ensembl:ENSMUSG00000025921 AllianceGenome:MGI:1924238
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    m366Asp; D1Ertd762e; 3110069K09Rik; 4921506A21Rik
    Summary
    Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within several processes, including chordate embryonic development; embryonic forelimb morphogenesis; and respiratory system development. Located in membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human RDH10 (retinol dehydrogenase 10). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 15.9), duodenum adult (RPKM 10.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rdh10 in Genome Data Viewer
    Location:
    1 A3; 1 4.94 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (16176106..16202774)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (16105882..16132550)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930444P10 gene Neighboring gene STARR-seq mESC enhancer starr_00336 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:16094431-16094614 Neighboring gene ribosomal protein L7 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:16167808-16168008 Neighboring gene staufen double-stranded RNA binding protein 2 Neighboring gene RIKEN cDNA C130013N14 gene Neighboring gene predicted gene 7568

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within animal organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within bud elongation involved in lung branching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within ear development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryonic camera-type eye development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryonic forelimb morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryonic organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within embryonic viscerocranium morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within metanephros development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within neural crest cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within nose development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of retinoic acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of retinoic acid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within primary lung bud formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in retinal metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retinal metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within retinoic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in retinol metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retinol metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within visual perception ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    retinol dehydrogenase 10
    NP_598593.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133832.3NP_598593.1  retinol dehydrogenase 10

      See identical proteins and their annotated locations for NP_598593.1

      Status: PROVISIONAL

      Source sequence(s)
      AC162442
      Consensus CDS
      CCDS14830.1
      UniProtKB/Swiss-Prot
      Q8CJ68, Q8VCH7
      Related
      ENSMUSP00000027053.8, ENSMUST00000027053.8
      Conserved Domains (2) summary
      cd05339
      Location:38307
      17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
      pfam00106
      Location:37252
      adh_short; short chain dehydrogenase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      16176106..16202774
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)