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    rcmE glutamate racemase [ Bacillus subtilis subsp. subtilis str. 168 ]

    Gene ID: 935934, updated on 4-Feb-2024

    Summary

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    Gene symbol
    rcmE
    Gene description
    glutamate racemase
    Locus tag
    BSU_28390
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bacillus subtilis subsp. subtilis str. 168 (strain: 168, sub-species: subtilis, type-material: type strain of Bacillus subtilis)
    Lineage
    Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus
    Old locus tag
    BSU28390
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    Genomic context

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    Sequence:
    NC_000964.3 (2903217..2904035, complement)

    NC_000964.3Genomic Context describing neighboring genes Neighboring gene ribonuclease PH Neighboring gene germination (cortex hydrolysis) and sporulation (stage II, multiple polar septa) lytic enzyme Neighboring gene putative transcriptional regulator (mother cell's gene expression during sporulation) Neighboring gene transcriptional regulator required for the expression of late spore coat genes

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000964.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substrate-induced conformational changes in Bacillus subtilis glutamate racemase and their implications for drug discovery. Ruzheinikov SN, et al. Structure, 2005 Nov. PMID 16271894
    2. Expression, purification and preliminary X-ray analysis of crystals of Bacillus subtilis glutamate racemase. Taal MA, et al. Acta Crystallogr D Biol Crystallogr, 2004 Nov. PMID 15502318
    3. Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement. Borriss R, et al. Microb Biotechnol, 2018 Jan. PMID 29280348, Free PMC Article
    4. An updated metabolic view of the Bacillus subtilis 168 genome. Belda E, et al. Microbiology (Reading), 2013 Apr. PMID 23429746
    5. From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Barbe V, et al. Microbiology (Reading), 2009 Jun. PMID 19383706, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The structure of a complex of RacE with D-glutamate reveals that the glutamate is buried in a deep pocket, whose formation at the interface of the enzyme's two domains involves a large-scale conformational rearrangement.
      Title: Substrate-induced conformational changes in Bacillus subtilis glutamate racemase and their implications for drug discovery.
    2. crystal structure of glutamate racemase
      Title: Expression, purification and preliminary X-ray analysis of crystals of Bacillus subtilis glutamate racemase.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    glutamate racemase
    NP_390717.2
    • Evidence 1c: Function from experimental evidences in the studied genus; PubMedId: 15347750, 17610893, 17720142, 19309142; Product type e: enzyme

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000964.3 Reference assembly

      Range
      2903217..2904035 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_390717.2 glutamate racemase [Bacillus subtilis subsp. subtilis str. 168]

      See identical proteins and their annotated locations for NP_390717.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A085C8L8, D4FZR3
      Conserved Domains (1) summary
      TIGR00067
      Location:6 → 256
      glut_race; glutamate racemase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P94556.2

    Gene LinkOut

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    Other Literature Sources
    Molecular Biology Databases