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    CDK10 cyclin dependent kinase 10 [ Homo sapiens (human) ]

    Gene ID: 8558, updated on 28-Oct-2024

    Summary

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    Official Symbol
    CDK10provided by HGNC
    Official Full Name
    cyclin dependent kinase 10provided by HGNC
    Primary source
    HGNC:HGNC:1770
    See related
    Ensembl:ENSG00000185324 MIM:603464; AllianceGenome:HGNC:1770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ALSAS; PISSLRE
    Summary
    The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
    Expression
    Ubiquitous expression in duodenum (RPKM 16.8), thyroid (RPKM 15.2) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See CDK10 in Genome Data Viewer
    Location:
    16q24.3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (89686689..89696354)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (95771455..95781117)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (89753097..89762762)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903758 Neighboring gene charged multivesicular body protein 1A Neighboring gene Neanderthal introgressed variant-containing enhancers experimental_46628 and experimental_46635 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7917 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7918 Neighboring gene spermatogenesis associated 33 Neighboring gene MPRA-validated peak2666 silencer Neighboring gene long intergenic non-protein coding RNA 2166 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7919 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:89765851-89766716 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7920 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7921 Neighboring gene spermatogenesis associated 2 like Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11418 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:89772795-89773295 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:89777095-89777658 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7922 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11419 Neighboring gene VPS9 domain containing 1 Neighboring gene VPS9D1 antisense RNA 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c-Raf/p-MEK/p-ERK signaling loop. Zhang X, et al. Mol Carcinog, 2024 Jan. PMID 37737453
    2. Molecular cloning of PISSLRE, a novel putative member of the cdk family of protein serine/threonine kinases. Brambilla R, et al. Oncogene, 1994 Oct. PMID 8084611
    3. The PISSLRE gene: structure, exon skipping, and exclusion as tumor suppressor in breast cancer. Crawford J, et al. Genomics, 1999 Feb 15. PMID 10036189
    4. CDK10 is not a target for aberrant DNA methylation in breast cancer. Heller G, et al. Anticancer Res, 2009 Oct. PMID 19846932
    5. CDK10 functions as a tumor suppressor gene and regulates survivability of biliary tract cancer cells. Yu JH, et al. Oncol Rep, 2012 Apr. PMID 22209942, Free PMC Article

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RNF115 aggravates tumor progression through regulation of CDK10 degradation in thyroid carcinoma.
      Title: RNF115 aggravates tumor progression through regulation of CDK10 degradation in thyroid carcinoma.
    2. CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c-Raf/p-MEK/p-ERK signaling loop.
      Title: CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c-Raf/p-MEK/p-ERK signaling loop.
    3. CDK10, CDK11, FOXO1, and FOXO3 Gene Expression in Alzheimer's Disease Encephalic Samples.
      Title: CDK10, CDK11, FOXO1, and FOXO3 Gene Expression in Alzheimer's Disease Encephalic Samples.
    4. A sib-pair with Al Kaissi syndrome caused by homozygosity for a novel CDK10 splice variant.
      Title: A sib-pair with Al Kaissi syndrome caused by homozygosity for a novel CDK10 splice variant.
    5. Functional characterization of the human Cdk10/Cyclin Q complex.
      Title: Functional characterization of the human Cdk10/Cyclin Q complex.
    6. Functional characterization of CDK10 and cyclin M truncated variants causing severe developmental disorders.
      Title: Functional characterization of CDK10 and cyclin M truncated variants causing severe developmental disorders.
    7. A large Canadian cohort provides insights into the genetic architecture of human hair colour.
      Title: A large Canadian cohort provides insights into the genetic architecture of human hair colour.
    8. Gene expression network analysis of lymph node involvement in colon cancer identifies AHSA2, CDK10, and CWC22 as possible prognostic markers.
      Title: Gene expression network analysis of lymph node involvement in colon cancer identifies AHSA2, CDK10, and CWC22 as possible prognostic markers.
    9. Association of Cyclin Dependent Kinase 10 and Transcription Factor 2 during Human Corneal Epithelial Wound Healing in vitro model.
      Title: Association of Cyclin Dependent Kinase 10 and Transcription Factor 2 during Human Corneal Epithelial Wound Healing in vitro model.
    10. The present study illustrated that downregulation of CDK10 expression activated Snaildriven EMT and consequently promoted glioma metastasis, suggesting that CDK10 may serve as a potential molecular target for glioma therapy.
      Title: Cyclin‑dependent kinase 10 prevents glioma metastasis via modulation of Snail expression.
    Submit: New GeneRIF Correction See all GeneRIFs (23)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Al Kaissi syndrome
    MedGen: C4540156 OMIM: 617694 GeneReviews: Not available
    		Compare labs

    EBI GWAS Catalog

    Description
    A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
    EBI GWAS Catalog
    Genome-wide association study identifies three loci associated with melanoma risk.
    EBI GWAS Catalog
    Genome-wide association study identifies three new melanoma susceptibility loci.
    EBI GWAS Catalog
    Identification of a melanoma susceptibility locus and somatic mutation in TET2.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    Tat tat FITC-labeled Tat 47-59 peptide downregulates gene expression of cyclin-dependent kinase 10 (CDK10) in U-937 macrophages PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell projection organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of cell population proliferation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cell cycle G2/M phase transition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in traversing start control point of mitotic cell cycle TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in ciliary basal body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cyclin-dependent protein kinase holoenzyme complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 10
    Names
    CDC2-related protein kinase
    cell division protein kinase 10
    cyclin-dependent kinase (CDC2-like) 10
    cyclin-dependent kinase related protein
    serine/threonine protein kinase PISSLRE
    NP_001092003.2
    NP_001153839.1
    NP_443713.2
    NP_443714.3
    XP_006721371.1
    XP_006721373.1
    XP_011521707.1
    XP_011521708.1
    XP_011521709.1
    XP_011521710.1
    XP_011521712.1
    XP_011521715.1
    XP_011521717.1
    XP_011521719.1
    XP_016879295.1
    XP_016879296.1
    XP_016879299.1
    XP_047290776.1
    XP_047290777.1
    XP_047290778.1
    XP_047290779.1
    XP_047290780.1
    XP_047290781.1
    XP_054170201.1
    XP_054170202.1
    XP_054170203.1
    XP_054170204.1
    XP_054170205.1
    XP_054170206.1
    XP_054170207.1
    XP_054170208.1
    XP_054170209.1
    XP_054170210.1
    XP_054170211.1
    XP_054170212.1
    XP_054170213.1
    XP_054170214.1
    XP_054170215.1
    XP_054170216.1
    XP_054170217.1
    XP_054170218.1
    XP_054170219.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098533.3 → NP_001092003.2  cyclin-dependent kinase 10 isoform c

      See identical proteins and their annotated locations for NP_001092003.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (c) uses an alternate donor splice site at the first exon resulting in translation from a downstream start codon, and uses an alternate donor splice site in the 3' coding region, compared to variant a. The resulting isoform (c) has a shorter N-terminus and lacks a 6-aa segment near the C-terminus, compared to isoform a.
      Source sequence(s)
      BC017342
      UniProtKB/TrEMBL
      F8W872
      Conserved Domains (1) summary
      cl21453
      Location:1 → 262
      PKc_like; Protein Kinases, catalytic domain

    2. NM_001160367.2 → NP_001153839.1  cyclin-dependent kinase 10 isoform d

      See identical proteins and their annotated locations for NP_001153839.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (d) uses an alternate donor splice site at the first exon resulting in translation from downstream start codon, compared to variant a. The resulting isoform (d) has a shorter N-terminus, compared to isoform a.
      Source sequence(s)
      AC010538, AK298386, BC017342
      UniProtKB/TrEMBL
      F8W872
      Conserved Domains (1) summary
      cd07845
      Location:1 → 268
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    3. NM_052987.4 → NP_443713.2  cyclin-dependent kinase 10 isoform b

      See identical proteins and their annotated locations for NP_443713.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (b) uses an alternate donor splice site at the first exon resulting in translation from a downstream start codon, and uses an alternate acceptor splice site at the last exon, compared to variant a. The resulting isoform (b) has a shorter N-terminus and a shorter and distinct C-terminus, compared to isoform a.
      Source sequence(s)
      BC017342, L33264
      Consensus CDS
      CCDS32514.2
      UniProtKB/TrEMBL
      F8W872
      Related
      ENSP00000424415.1, ENST00000505473.5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 257
      PKc_like; Protein Kinases, catalytic domain

    4. NM_052988.5 → NP_443714.3  cyclin-dependent kinase 10 isoform a

      See identical proteins and their annotated locations for NP_443714.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (a) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AK298386, BC017342
      Consensus CDS
      CCDS10984.2
      UniProtKB/Swiss-Prot
      A8K370, A8K8I6, A8MXU6, B3KQJ3, B7Z420, D3DX82, D3DX83, Q0VGZ7, Q15130, Q15131, Q6PJC0
      UniProtKB/TrEMBL
      B7Z537
      Related
      ENSP00000338673.7, ENST00000353379.12
      Conserved Domains (1) summary
      cd07845
      Location:31 → 339
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    RNA

    1. NR_027702.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (e) lacks the second exon, compared to variant a. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant a, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK296631, AK298386, BC017342
      Related
      ENST00000510811.6

    2. NR_027703.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: Transcript Variant: This variant (f) lacks the second exon and uses an alternate acceptor splice site at the last exon, compared to variant a. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant a, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK298386, BC025301

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      89686689..89696354
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011523405.4 → XP_011521707.1  cyclin-dependent kinase 10 isoform X1

      UniProtKB/TrEMBL
      B7Z537
      Conserved Domains (2) summary
      cd07845
      Location:31 → 371
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
      PTZ00024
      Location:43 → 368
      PTZ00024; cyclin-dependent protein kinase; Provisional

    2. XM_011523407.4 → XP_011521709.1  cyclin-dependent kinase 10 isoform X3

      UniProtKB/TrEMBL
      B7Z537
      Conserved Domains (2) summary
      cd07845
      Location:31 → 360
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
      PTZ00024
      Location:43 → 360
      PTZ00024; cyclin-dependent protein kinase; Provisional

    3. XM_011523406.4 → XP_011521708.1  cyclin-dependent kinase 10 isoform X2

      UniProtKB/TrEMBL
      B7Z537
      Conserved Domains (2) summary
      cd07845
      Location:31 → 365
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
      PTZ00024
      Location:43 → 362
      PTZ00024; cyclin-dependent protein kinase; Provisional

    4. XM_011523408.4 → XP_011521710.1  cyclin-dependent kinase 10 isoform X4

      UniProtKB/TrEMBL
      B7Z537
      Conserved Domains (2) summary
      cd07845
      Location:31 → 354
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
      PTZ00024
      Location:43 → 354
      PTZ00024; cyclin-dependent protein kinase; Provisional

    5. XM_006721310.4 → XP_006721373.1  cyclin-dependent kinase 10 isoform X7

      UniProtKB/TrEMBL
      B7Z537
      Related
      ENST00000505733.5
      Conserved Domains (2) summary
      cd07845
      Location:31 → 328
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
      PLN00009
      Location:38 → 325
      PLN00009; cyclin-dependent kinase A; Provisional

    6. XM_006721308.4 → XP_006721371.1  cyclin-dependent kinase 10 isoform X6

      UniProtKB/TrEMBL
      B7Z537
      Conserved Domains (1) summary
      cd07845
      Location:31 → 333
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    7. XM_017023807.3 → XP_016879296.1  cyclin-dependent kinase 10 isoform X9

      UniProtKB/TrEMBL
      B7Z537

    8. XM_011523415.3 → XP_011521717.1  cyclin-dependent kinase 10 isoform X11

      See identical proteins and their annotated locations for XP_011521717.1

      UniProtKB/TrEMBL
      F8W872
      Conserved Domains (1) summary
      cd07845
      Location:1 → 300
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    9. XM_011523410.3 → XP_011521712.1  cyclin-dependent kinase 10 isoform X11

      See identical proteins and their annotated locations for XP_011521712.1

      UniProtKB/TrEMBL
      F8W872
      Conserved Domains (1) summary
      cd07845
      Location:1 → 300
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    10. XM_017023806.2 → XP_016879295.1  cyclin-dependent kinase 10 isoform X5

      UniProtKB/TrEMBL
      F8W872
      Conserved Domains (2) summary
      cd07845
      Location:16 → 334
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
      PTZ00024
      Location:16 → 331
      PTZ00024; cyclin-dependent protein kinase; Provisional

    11. XM_047434820.1 → XP_047290776.1  cyclin-dependent kinase 10 isoform X8

    12. XM_047434821.1 → XP_047290777.1  cyclin-dependent kinase 10 isoform X10

      Related
      ENSP00000329957.8, ENST00000331006.12

    13. XM_047434825.1 → XP_047290781.1  cyclin-dependent kinase 10 isoform X13

    14. XM_047434824.1 → XP_047290780.1  cyclin-dependent kinase 10 isoform X12

    15. XM_011523417.4 → XP_011521719.1  cyclin-dependent kinase 10 isoform X15

      Conserved Domains (2) summary
      smart00220
      Location:39 → 225
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:31 → 223
      PKc_like; Protein Kinases, catalytic domain

    16. XM_017023810.2 → XP_016879299.1  cyclin-dependent kinase 10 isoform X14

      UniProtKB/TrEMBL
      F8W872
      Conserved Domains (1) summary
      cl21453
      Location:1 → 257
      PKc_like; Protein Kinases, catalytic domain

    17. XM_011523413.3 → XP_011521715.1  cyclin-dependent kinase 10 isoform X11

      See identical proteins and their annotated locations for XP_011521715.1

      UniProtKB/TrEMBL
      F8W872
      Conserved Domains (1) summary
      cd07845
      Location:1 → 300
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    18. XM_047434822.1 → XP_047290778.1  cyclin-dependent kinase 10 isoform X11

    19. XM_047434823.1 → XP_047290779.1  cyclin-dependent kinase 10 isoform X11

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      95771455..95781117
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054314226.1 → XP_054170201.1  cyclin-dependent kinase 10 isoform X1

    2. XM_054314228.1 → XP_054170203.1  cyclin-dependent kinase 10 isoform X3

    3. XM_054314227.1 → XP_054170202.1  cyclin-dependent kinase 10 isoform X2

    4. XM_054314229.1 → XP_054170204.1  cyclin-dependent kinase 10 isoform X4

    5. XM_054314232.1 → XP_054170207.1  cyclin-dependent kinase 10 isoform X7

    6. XM_054314231.1 → XP_054170206.1  cyclin-dependent kinase 10 isoform X6

    7. XM_054314234.1 → XP_054170209.1  cyclin-dependent kinase 10 isoform X9

    8. XM_054314239.1 → XP_054170214.1  cyclin-dependent kinase 10 isoform X11

    9. XM_054314236.1 → XP_054170211.1  cyclin-dependent kinase 10 isoform X11

    10. XM_054314230.1 → XP_054170205.1  cyclin-dependent kinase 10 isoform X5

    11. XM_054314233.1 → XP_054170208.1  cyclin-dependent kinase 10 isoform X8

    12. XM_054314235.1 → XP_054170210.1  cyclin-dependent kinase 10 isoform X10

    13. XM_054314242.1 → XP_054170217.1  cyclin-dependent kinase 10 isoform X13

    14. XM_054314241.1 → XP_054170216.1  cyclin-dependent kinase 10 isoform X12

    15. XM_054314244.1 → XP_054170219.1  cyclin-dependent kinase 10 isoform X15

    16. XM_054314243.1 → XP_054170218.1  cyclin-dependent kinase 10 isoform X14

    17. XM_054314238.1 → XP_054170213.1  cyclin-dependent kinase 10 isoform X11

    18. XM_054314237.1 → XP_054170212.1  cyclin-dependent kinase 10 isoform X11

    19. XM_054314240.1 → XP_054170215.1  cyclin-dependent kinase 10 isoform X11

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_003674.2: Suppressed sequence

      Description
      NM_003674.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q15131.1 GenPept UniProtKB/Swiss-Prot:Q15131

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