Smarcd2 SWI/SNF related BAF chromatin remodeling complex subunit D2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Smarcd2provided by RGD
Official Full Name: SWI/SNF related BAF chromatin remodeling complex subunit D2provided by RGD
Primary source: RGD:69289
See related: EnsemblRapid:ENSRNOG00000010557 AllianceGenome:RGD:69289
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: BAF60b
Summary: Predicted to enable transcription coregulator activity. Predicted to be involved in nucleosome disassembly and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of SWI/SNF complex. Predicted to be active in nucleus. Orthologous to human SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 439.9), Adrenal (RPKM 360.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q32.1

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (91693542..91702408, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (91193752..91202817, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (94451866..94460732, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

M60510 (e-PCR)
- UniSTS:124962

RH144361 (e-PCR)
- UniSTS:233606

RH136975 (e-PCR)
- UniSTS:219064

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables transcription coregulator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in chromatin remodeling	ISO Inferred from Sequence Orthology more info
involved_in nucleosome disassembly	IEA Inferred from Electronic Annotation more info
involved_in nucleosome disassembly	ISO Inferred from Sequence Orthology more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of SWI/SNF complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SWI/SNF complex	IEA Inferred from Electronic Annotation more info
part_of SWI/SNF complex	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

Names: 60 kDa BRG-1/Brm-associated factor subunit B; BRG1-associated factor 60B; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_031983.2 → NP_114189.1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

See identical proteins and their annotated locations for NP_114189.1

Status: PROVISIONAL

Source sequence(s)

BC062063

UniProtKB/Swiss-Prot

O54771, O54772

UniProtKB/TrEMBL

A0A8L2Q6R2, A6HK23

Related

ENSRNOP00000095674.2, ENSRNOT00000108911.2

Conserved Domains (2) summary

TIGR01628
Location:43 → 148

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

cd17675
Location:307 → 386

SWIB_BAF60B; SWIB domain found in BRG1-associated factor 60B (BAF60B) and similar proteins